Resistance Training and Sex Hormone Concentrations During the Menstrual Cycle

NCT ID: NCT04163380

Last Updated: 2020-02-18

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 25 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-11-01
• Study Completion Date: 2021-12-31

Brief Summary

Although there are numerous studies showing effects of aerobic training on sex hormone concentrations, research analyzing the fluctuation of sex hormones in response to resistance training (RT) is lacking. The objective of this project is to analyze estradiol (E2) and progesterone (P4) responses to an acute resistance training session throughout different phases of the menstrual cycle. This proposed research has strong implications for exercise prescription and for women in general, but more importantly will allow exercise physiologists, coaches, personal trainers, or nutritionists optimize exercise programming around women's menstrual cycle.

Conditions

Women's Health

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Early Follicular Phase (EFP)

Group Type: EXPERIMENTAL

Resistance Training

Intervention Type: BEHAVIORAL

Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest

Late Follicular Phase (LFP)

Group Type: EXPERIMENTAL

Resistance Training

Intervention Type: BEHAVIORAL

Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest

Early Luteal Phase (ELP)

Group Type: EXPERIMENTAL

Resistance Training

Intervention Type: BEHAVIORAL

Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest

Late Luteal Phase (LLP)

Group Type: EXPERIMENTAL

Resistance Training

Intervention Type: BEHAVIORAL

Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest

Interventions

Resistance Training

Participants will exercise at the mid-point of each menstrual cycle phase (EFP- day 4, LFP- day 11, ELP- day 18 and LLP- day 25 for a 28 day menstrual cycle). Training will consist of a warm up. Intensity will be set at 70% of 1RM, and the circuit training will include 7 strength exercises: leg press, rows, back squat, weighted crunches, deadlifts, bench press, and weighted squat jumps. The participant will perform 3 sets f 10 repetitions with 30 seconds of rest

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Eumenorrheic females
• Age 18-45 years old
• BMI of 18.5-34.99 kg/m2

Exclusion Criteria

• Practice exercise more than 2 days/week in the last 3 months.
• Cardiovascular, metabolic, pulmonary or muscular-skeletal condition
• Taking medications that affect metabolism (e.g. oral contraceptives)
• Irregular menstrual cycles

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Southern Illinois University Edwardsville

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Southern Illinois University Edwardsville

Edwardsville, Illinois, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Maria Fernandez del Valle, PhD

Role: CONTACT

marfern@siue.edu

6186505905

Facility Contacts

Maria Fernandez del Valle, PhD

Role: primary

marfern@siue.edu

618-650-5905

Other Identifiers

111B

Identifier Type: -

Identifier Source: org_study_id