Effect of an Exercise on Serum Uncoupling Protein-1 Level and the Role of Uncoupling Protein-1-3826 A/G Polymorphism
NCT ID: NCT04156113
Last Updated: 2020-09-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
86 participants
INTERVENTIONAL
2019-11-11
2020-09-07
Brief Summary
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Therefore, this study hypothesizes that:
H01: Sedentary people and athletes' serum uncoupling protein 1, irisin, and interleukine 6 levels are different before and after an acute maximal exercise.
H02: Sedentary people and athletes' basal serum uncoupling protein 1 levels are associated with uncoupling protein 1-3826 A/G polymorphism.
H03: Uncoupling protein 1-3826 A/G polymorphism has a modifying role in the effect of maximal exercise on serum uncoupling protein 1 levels.
H04: Sedentary people and athletes' basal serum lipid and lipoprotein levels are associated with uncoupling protein 1-3826 A/G polymorphism.
H05: Uncoupling protein 1-3826 A / G polymorphism has a modifying role in the effect of maximal exercise on serum lipid and lipoprotein levels.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Athletes Group
The athletes group will be composed of healthy, non obese (body mass index \< 30), male basketball, volleyball and handball players aged between 18 and 35 years who have been training regularly for at least 3 months. Participants must not be regular consumer of cigarettes, alcohol, drugs and antioxidant substances.
Intervention: Yo-Yo intermittent recovery test (level 1) is administered.
Yo-Yo intermittent recovery test (level 1)
The Yo-Yo intermittent recovery test (level 1) will be administered once.
Sedentary Group
The sedentary group will be composed of healthy, non obese (body mass index \< 30), male aged between 18 and 35 years who have not been training regularly for at least 3 months. Participants must not be regular consumer of cigarettes, alcohol, drugs and antioxidant substances.
Intervention: Yo-Yo intermittent recovery test (level 1) is administered.
Yo-Yo intermittent recovery test (level 1)
The Yo-Yo intermittent recovery test (level 1) will be administered once.
Interventions
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Yo-Yo intermittent recovery test (level 1)
The Yo-Yo intermittent recovery test (level 1) will be administered once.
Eligibility Criteria
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Inclusion Criteria
* Must be basketball, or volleyball, or handball players.
* Must be subjects who have been training regularly for at least 3 months.
* Sedentary group:
\* Must be subjects who have not been training regularly for at least 3 months.
* For both groups:
* Healthy.
* Non obese (body mass index \< 30).
* Aged between 18 and 35 years.
Exclusion Criteria
* Being regular consumer of cigarettes, alcohol, drugs and antioxidant substances.
* Being obese (body mass index \> 30).
* Having an acute or chronic injury which is limiting physical performance.
* Having a disease (anemia, infection...) detected from the biochemical analysis of the blood samples.
* Being injured or sick during the study.
18 Years
35 Years
MALE
Yes
Sponsors
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Ege University
OTHER
Eastern Mediterranean University
OTHER
Responsible Party
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Jeffry Roy Chauchat
Senior instructor
Principal Investigators
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Faruk Turgay, Assoc. Prof
Role: STUDY_CHAIR
Ege University, Faculty of Sports Science
Locations
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Ege University Faculty of Sport Sciences
Izmir, , Turkey (Türkiye)
Countries
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Other Identifiers
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18-10.2/56
Identifier Type: -
Identifier Source: org_study_id
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