Predictors of Intracranial Hemorrhage in ARDS Patients on ECMO

NCT ID: NCT04142775

Last Updated: 2019-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-02-01

Study Completion Date

2020-03-31

Brief Summary

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Intracranial hemorrhage is is a rare, but critical incident in patients with acute lung failure undergoing ECMO therapy. Predictors of intracranial hemorrhage are yet to be defined to identify patients at (high) risk. This retrospective analysis investigates the predictive value and validity of parameters and specific risk factors of critically ill ARDS patients treated with ECMO.

Detailed Description

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Conditions

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ARDS, Human Extracorporeal Membrane Oxygenation Complication

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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intracranial hemorrhage (ICH)

ARDS patients treated with ECMO developing ICH

complication versus no complication

Intervention Type OTHER

development of ICH

no intracranial hemorrhage

ARDS patients treated with ECMO not developing ICH

No interventions assigned to this group

Interventions

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complication versus no complication

development of ICH

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ARDS following Berlin definition (mild, moderate, severe)
* ECMO therapy (veno-venous cannulation)

Exclusion Criteria

* ECMO, other than VV
* ICH at initiation of ECMO
* no cerebral CT scan at any time
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Mario Menk

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Charite university medicine Berlin

Berlin, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Mario Menk, PD Dr med

Role: CONTACT

+4930450551002

Facility Contacts

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Mario Menk, PD Dr med

Role: primary

+4930450551002

Oliver Hunsicker, Dr med

Role: backup

+4930450551002

Other Identifiers

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ChariteMM

Identifier Type: -

Identifier Source: org_study_id

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