A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Autism

NCT ID: NCT04100863

Last Updated: 2025-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-02

Study Completion Date

2030-06-30

Brief Summary

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This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding autism.

Detailed Description

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The goal of this Research Study is to better understand how the genetic information in subject's microbiome correlates to the information provided in surveys and in medical records regarding autism.

Conditions

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Autism Autism Spectrum Disorder Autistic Disorder Autism, Akinetic Autism; Atypical Autism; Psychopathy Autism Fragile Syndrome X Autism With High Cognitive Abilities Autism-Related Speech Delay Autism, Susceptibility to, 6 Autism Spectrum Disorder High-Functioning Autistic Thinking Autism, Susceptibility to, X-Linked 6 Autistic Behavior

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Individuals with Autism

Individuals who have been diagnosed with autism

No Intervention

Intervention Type OTHER

There is no intervention for this study.

Interventions

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No Intervention

There is no intervention for this study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Signed informed consent by parent or legally authorized representative
2. Male or female patients age 6 and older.
3. Diagnosis of autism per DSM-V criteria (See appendix)

Exclusion Criteria

1. Refusal by parent or legally authorized representative to sign informed consent form
2. Treatment with antibiotics within 2 weeks prior to screening
3. Treatment with probiotics within 6 weeks prior to screening
4. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy.
5. Postoperative stoma, ostomy, or ileoanal pouch
6. Participation in any experimental drug protocol within the past 12 weeks
7. Treatment with total parenteral nutrition
8. Any clinically significant evidence of disease that could interfere with the subject's ability to enter the trial
9. Inability of parent or legally authorized representative to adequately communicate with the investigator or their respective designee and/or comply with the requirements of the entire study
Minimum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ProgenaBiome

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sabine Hazan, MD

Role: PRINCIPAL_INVESTIGATOR

ProgenaBiome

Locations

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ProgenaBiome

Ventura, California, United States

Site Status

Countries

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United States

Other Identifiers

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PRG-006

Identifier Type: -

Identifier Source: org_study_id

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