The Effect of Epidural Anesthesia on the Optic Nerve Sheath Diameter in Preeclampsia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

22 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-14

Study Completion Date

2023-05-19

Brief Summary

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This study aims to assess the effect of epidural anesthesia on the optic nerve sheath diameter in parturients with preeclampsia.

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Detailed Description

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This prospective observational study will be performed in parturients, either with or without preeclampsia, who scheduled to undergo elective cesarean delivery under epidural anesthesia. Epidural anesthesia will be done according to the standard technique. Optic nerve sheath diameter (ONSD) will be measured before and after the epidural injection of anesthetic solutions using ultrasonography. The investigators will assess whether epidural anesthesia has effect on optic nerve sheath diameter of pregnant women, and the investigators will also compare ONSD between healthy parturients and parturients with preeclampsia. The investigators will evaluate the relationship between ONSD and disease severity of preeclampsia.

Conditions

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Preeclampsia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Parturients with preeclampsia

Parturients who were diagnosed with preeclampsia

Epidural anesthesia

Intervention Type PROCEDURE

Epidural anesthesia using standardized technique

Healthy parturients

Healthy full-term parturients

Epidural anesthesia

Intervention Type PROCEDURE

Epidural anesthesia using standardized technique

Interventions

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Epidural anesthesia

Epidural anesthesia using standardized technique

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled to undergo planned cesarean section under epidural anesthesia if they have a singleton pregnancy, complicated by severe preeclampsia.

Severe preeclampsia was defined using the American College of Obstetricians and Gynecologist Task Force on Hypertension in Pregnancy recommendations

* Controls will be healthy pregnant women at term (\>37 weeks), with a singleton pregnancy, no signs or symptoms of preeclampsia and no intrauterine fetal growth restriction, who are planned to undergo elective cesarean delivery under epidural anesthesia

Exclusion Criteria

* Contraindication to epidural anesthesia
* Morbid cardiovascular disease
* Cerebrovascular disease
* Known fetal anomaly
* Any signs of onset of labor
* Body weight \< 40 kg or body weight \> 100 kg
* Height \< 140cm or height \> 190cm
* eye disease
* infection or trauma near the eyes
* abnormality of intracranial pressure due to Intracranial pathology

Minimum Eligible Age

19 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No