Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness

NCT ID: NCT04092036

Last Updated: 2019-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-15

Study Completion Date

2020-03-14

Brief Summary

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The aim of the study to examine Optic Nerve Sheath Diameter measurement for prediction of fluid responsiveness in hemodynamically unstable patients

Detailed Description

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Conditions

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Fluid Responsiveness Optic Nerve Sheath Diameter Shock

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Unstable patients

Patients on mechanical ventilation, 18 years or older and developing hypotension (Mean arterial blood pressure) \<65 mmHg

Optic Nerve Sheath Diameter (ONSD) measurement by ultrasound

Intervention Type DEVICE

ONSD measurements will be performed in the supine patient. Ultrasound gel will be applied over the closed upper eyelid. The ultrasound probe will be placed on the temporal area of the eyelid. Then the probe will be angled in order to display the entry of the optic nerve into the globe.

ONSD will be measured 3 mm behind the globe in the transverse plane perpendicular to the optic nerve. For each optic nerve three measurements will be made. The ONSD corresponds to the mean of the six values which will be obtained from each patient (three measurements for each eye).

Interventions

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Optic Nerve Sheath Diameter (ONSD) measurement by ultrasound

ONSD measurements will be performed in the supine patient. Ultrasound gel will be applied over the closed upper eyelid. The ultrasound probe will be placed on the temporal area of the eyelid. Then the probe will be angled in order to display the entry of the optic nerve into the globe.

ONSD will be measured 3 mm behind the globe in the transverse plane perpendicular to the optic nerve. For each optic nerve three measurements will be made. The ONSD corresponds to the mean of the six values which will be obtained from each patient (three measurements for each eye).

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients on mechanical ventilation
* 18 years or older
* patients developing hypotension (Mean arterial blood pressure) \<65 mmHg

Exclusion Criteria

* Patients with Spontaneously breathing activity.
* Patients with a history of intracranial disease e.g. (stroke, TBI, causes of increased intracranial pressure).
* local cause in the eye as (Glaucoma, Single eye)
* Need for high PEEP.
* Known history of cardiac disease.
* Organ/s failure at admission
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Hadeel Ibraheim Elsagheir

Resident at Anesthesiology, Surgical ICU and Pain Medicine Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Hadeel Ibraheim Elsagheir, MBBCH

Role: CONTACT

00201090884208

Other Identifiers

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33157/06/19

Identifier Type: -

Identifier Source: org_study_id

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