Treatment of Tooth Sensitivity With the Use of Biorepair Toothpaste

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

72 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-18

Study Completion Date

2019-08-26

Brief Summary

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The purpose of this clinical study is to evaluate the effect of desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals in reducing or controlling DH after 8 weeks of treatment

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Detailed Description

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This clinical study design is an 8-week single center, before and after use of desensitize dentifrice. This study will conducted in the College of Dentistry Qassim University. 72 patients surfing from DH, include in the study fulfill the inclusion criteria. All subjects 20 to 70 years of age in good health, and must have 2 teeth with DH, will be included in this study. Screening will be performed for the selection of patients, which fulfill the inclusion criteria. Baseline data will be recorded and Sensitivity was assessed by air-blast sensitivity, using Schiff Sensitivity Scale (SSS).

Sensitivity was assessed by air-blast sensitivity, using Schiff Sensitivity Scale (SSS) described as follows.

0 = Subject does not respond to air stimulus

1. = Subject responds to air stimulus but does not request discontinuation of stimulus
2. = Subject responds to air stimulus and requests discontinuation or moves from stimulus
3. = Subject responds to air stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus

Conditions

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Dentinal Hypersensitivity

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Clinical trials with a single arm: Participants will be treated with desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals (Zn-CHA) for 8 weeks.

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Clinical trials with a single arm

: Participants will be treated with desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals (Zn-CHA) for 8 weeks.

Group Type EXPERIMENTAL

Single arm clinical study

Intervention Type OTHER

Participants will be treated with desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals (Zn-CHA) for 8 weeks.

Interventions

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Single arm clinical study

Participants will be treated with desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals (Zn-CHA) for 8 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All male and female subjects 20 to 70 years of age
* All subjects in good health
* All subjects must have 2 teeth with DH, only incisors, canine and premolars were included with the exposed cervical dentin (facial surfaces).

All participants of the study having Schiff Sensitivity Scale score of 2 \& 3

Exclusion Criteria

* Subjects with deep carious teeth, defective restorations
* Any pathological lesion
* Periodontal disease, mobile teeth, cracked enamel, orthodontic appliances,
* Periodontal pockets \>4mm
* Subjects using pain control medicines, sensitive toothpaste
* Pregnant or lactating women

Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes