Senescent Immunity in Elders and Vaccine Responses (SILVER)
NCT ID: NCT04077424
Last Updated: 2022-07-12
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE4
10 participants
INTERVENTIONAL
2019-10-21
2020-02-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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Fluzone-High Dose
FDA approved high dose inactivated influenza vaccine (HD-Fluzone)
Fluzone-High Dose Quadrivalent
Seasonal influenza vaccination with FDA approved vaccines for this age group.
Fluad
Adjuvanted (MF59) inactivated influenza vaccine (Fluad)
Fluad
Adjuvanted (MF59) inactivated influenza vaccine
Recombinant Hemagglutinin vaccine (Flublok)
Recombinant hemagglutinin vaccine
Flublock
Recombinant hemagglutinin vaccine
Interventions
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Fluzone-High Dose Quadrivalent
Seasonal influenza vaccination with FDA approved vaccines for this age group.
Fluad
Adjuvanted (MF59) inactivated influenza vaccine
Flublock
Recombinant hemagglutinin vaccine
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Independent Living (including Assisted Living)
Exclusion Criteria
* Allergic to any vaccine components, excluding eggs.
* History of Guillain-Barre.
* Residing in a long -term care facility such as a nursing home.
65 Years
125 Years
ALL
Yes
Sponsors
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Vanderbilt University Medical Center
OTHER
Responsible Party
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Spyros Kalams
Associate Professor Infectious Disease
Principal Investigators
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Spyros Kalams
Role: PRINCIPAL_INVESTIGATOR
Vanderbilt University Medical Center
Locations
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Vanderbilt University Medical Center
Nashville, Tennessee, United States
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Document Type: Informed Consent Form
Other Identifiers
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single cell
Identifier Type: -
Identifier Source: org_study_id
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