Salvage Living Donor Liver Transplantation for HCC Beyond All Criteria Yield Equivalent Results to Milan Criteria
NCT ID: NCT04069416
Last Updated: 2019-08-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
241 participants
OBSERVATIONAL
2004-01-31
2019-01-31
Brief Summary
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Detailed Description
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HEPATOCELLULAR CARCINOMA (HCC) is the second leading cause of cancer mortality worldwide. Living donor liver transplantation (LDLT) for HCC patients has emerged as a rewarding therapy for a cure and a successful alternative where a Deceased donor liver transplantation (DDLT) program is lacking. Therefore, trials for careful expansion to Milan criteria have been adopted.
Aim of the study:
To evaluate the impact of expanding criteria beyond Milan on tumor recurrence and patient survival that will help identify the best selection criteria for HCC transplanted patients
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Group I
175 patients who fall within the Milan criteria.
living donor liver transplantation
liver graft from a living donor
Group II
36 patients who fall within up-to-7 criteria
living donor liver transplantation
liver graft from a living donor
Group III
30 patients beyond up-to-7 criteria and will be termed beyond all criteria (BAC).
living donor liver transplantation
liver graft from a living donor
Interventions
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living donor liver transplantation
liver graft from a living donor
Eligibility Criteria
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Inclusion Criteria
* age\>18y
Exclusion Criteria
* patient not fit for surgery
* age \>70y
18 Years
70 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Manar Salah
Principal investigator
Other Identifiers
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68954200
Identifier Type: -
Identifier Source: org_study_id
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