Leuven Interactive Scheme for hearingTraining Evaluation, and Audiological Rehabilitation

NCT ID: NCT04063748

Last Updated: 2023-02-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2024-04-30

Brief Summary

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It is believed that persons with hearing impairment benefit from auditory rehabilitation (AR), i.e. regular assessment and training of their listening skills. However, the efficacy of auditory rehabilitation has not been investigated before. In Leuven (Belgium) an e-health app has been developed that enables performance assessment, listening skills training, and counselling for persons with hearing impairment. Currently, an RCT is prepared to evaluate the different modules in persons with hearing impairment. The experimental group will receive auditory rehabilitation training modules, and a control group will either receive training tasks that are NOT believed to transfer to improved listening skills or will not receive any training (passive control).

1. Do participants improve on the trained tasks in the LUISTER AR scheme and does this improvement transfer to an improvement in speech perception in noise (primary outcome), executive functioning and/or quality of life (secondary outcomes)?
2. Does training with the LUISTER AR scheme provide more benefit on primary and secondary outcomes than a placebo program (active control group) or no training (passive control group)?
3. Can improvement in speech in noise perception, obtained with the LUISTER AR scheme, be consolidated until 6 months after training has stopped?
4. Are certain user-specific or training-specific aspects correlated to improvement on task-specific learning as well as near- and far transfer

Detailed Description

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Goals of the study:

To determine an optimal, personalized AR scheme (considering age, degree of HI) and possible interacting factors (e.g., training time, type of errors)

To investigate transfer of auditory and auditory-cognitive training to listening skills in everyday life

To develop evidence-based guidelines for clinical AR

A study to assess the efficacy in CI users will start with baseline assessment (speech in noise understanding, LIST sentences and cognitive tests (executive functioning, important for listening skills). This will be followed by 8 weeks of training, an intermediate assessment moment, again 8 weeks of training, and a final evaluation moment. After 6 months follow-up evaluation to investigate retention. This study is comprised of an active training group and an active control group.

A study to assess the efficacy in HA users will start with baseline assessment (speech in noise understanding, LIST sentences and cognitive tests (executive functioning, important for listening skills). This will be followed by 6 weeks of training, an intermediate (online) assessment moment, again 6 weeks of training, and a final evaluation moment.

Conditions

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Hearing Disability

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants are assigned to either the test or the placebo group.
Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
The participant does not know whether (s)he receives treatment or placebo. The investigator and the outcomes assessor are blind to this information too. The care provide (speech therapist) would know after communication with the participant.

In case of the HA-study, participants either receive an intervention or do not receive an intervention. Therefore, they cannot be masked.

Study Groups

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Experimental

Participants are asked to train (at least) 5 times a week during 15 - 20 mins. The first 4 sessions are training sessions, the fifth session is an in-training test session (DTT and phoneme discrimination).

Group Type EXPERIMENTAL

Audiological rehabilitation

Intervention Type BEHAVIORAL

Experimental: tablet-based take-home auditory-cognitive training, which consists of phoneme tasks, words in quiet and in different types of noise

Placebo

CI-users: Participants are asked to train (at least) 5 times a week during 15 - 20 mins. The first 4 sessions are training sessions, and the fifth session is an in-training test session (DTT and phoneme discrimination).

Group Type OTHER

Placebo Rehabilitation

Intervention Type BEHAVIORAL

CI-users: Placebo, tablet-based take-home psychophysical tasks, reading (non auditory)

Passive Control

HA users: Participants do not receive an intervention.

Group Type PLACEBO_COMPARATOR

Passive Control

Intervention Type BEHAVIORAL

No intervention in the passive control group for HA-users.

Interventions

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Audiological rehabilitation

Experimental: tablet-based take-home auditory-cognitive training, which consists of phoneme tasks, words in quiet and in different types of noise

Intervention Type BEHAVIORAL

Placebo Rehabilitation

CI-users: Placebo, tablet-based take-home psychophysical tasks, reading (non auditory)

Intervention Type BEHAVIORAL

Passive Control

No intervention in the passive control group for HA-users.

Intervention Type BEHAVIORAL

Other Intervention Names

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LUISTER

Eligibility Criteria

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Inclusion Criteria

* hearing impaired
* sufficient knowledge of the Dutch language

Exclusion Criteria

* cognitively impaired
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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KU Leuven

OTHER

Sponsor Role collaborator

Universitaire Ziekenhuizen KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Astrid Van Wieringen, PhD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Astrid van Wieringen

Role: PRINCIPAL_INVESTIGATOR

KU Leuven

Locations

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KU Leuven, Experimental ORL, Dept Neurosciences

Leuven, Vlaams Brabant, Belgium

Site Status

Countries

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Belgium

References

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Magits S, Boon E, De Meyere L, Dierckx A, Vermaete E, Francart T, Verhaert N, Wouters J, van Wieringen A. Comparing the Outcomes of a Personalized Versus Nonpersonalized Home-Based Auditory Training Program for Cochlear Implant Users. Ear Hear. 2023 May-Jun 01;44(3):477-493. doi: 10.1097/AUD.0000000000001295. Epub 2022 Oct 29.

Reference Type DERIVED
PMID: 36534665 (View on PubMed)

van Wieringen A, Wouters J. Lilliput: speech perception in speech-weighted noise and in quiet in young children. Int J Audiol. 2023 Aug;62(8):747-755. doi: 10.1080/14992027.2022.2086491. Epub 2022 Jun 22.

Reference Type DERIVED
PMID: 35732012 (View on PubMed)

Related Links

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Other Identifiers

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S59845

Identifier Type: -

Identifier Source: org_study_id

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