Pilot Study of a Decision Aid Intervention for Family-building After Cancer

NCT ID: NCT04059237

Last Updated: 2024-04-09

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

102 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-06

Study Completion Date

2022-12-11

Brief Summary

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This study tests a web-based decision aid and planning too to help young female cancer survivors manage fertility and family-building issues in post treatment survivorship.

Detailed Description

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The overall goal of this work is to pilot test a single-arm intervention of a decision aid and planning tool (website) to assist young adult female cancer survivors in making decisions and preparing for family-building after cancer.

Primary Objective: Examine feasibility and acceptability of a decision aid intervention in a single-arm pilot trial.

Secondary Objective: Obtain preliminary effect sizes of the decision aid intervention using a pre-post study design.

Conditions

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Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Online Decision Aid

web-based psychosocial assessment questionnaires will be administered at baseline (T1; pre-intervention) and at one-month (T2) and three-month (T3) follow-up time points.

Group Type EXPERIMENTAL

Web based decision aid intervention

Intervention Type BEHAVIORAL

Decision aid tool (website) to assist young adult female cancer survivors in making decisions and preparing for family-building after cancer.

Interventions

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Web based decision aid intervention

Decision aid tool (website) to assist young adult female cancer survivors in making decisions and preparing for family-building after cancer.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Female
* Completed cancer treatment known to have gonadotoxic effects (e.g., systemic chemotherapy, surgery affecting reproductive organs or hormone regulation, and/or pelvic radiation)
* Understands verbal and written English
* Desires future children or uncertainty regarding family-building plans
* Access to the Internet and use of a computer, tablet, or smartphone

Exclusion Criteria

* Currently undergoing cancer treatment excluding long-term adjuvant or maintenance therapies, such as tamoxifen
* Significant physical or mental disability that prevents completion of study activities

Note: Survivors on adjuvant maintenance or endocrine treatment, such as tamoxifen, will not be excluded because clinical guidelines allow treatment delay or hiatus to accommodate fertility preservation, egg extraction for surrogacy, or pregnancy for some patients, and because patients may be interested in alternative family-building options such as surrogacy or adopting.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Catherine Benedict

Clinical Associate Professor, Psychiatry and Behavioral Sciences- Medical Psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Catherine Benedict

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Locations

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Stanford Cancer Center

Stanford, California, United States

Site Status

Countries

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United States

References

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Benedict C, Ford JS, Schapira L, Simon P, Spiegel D, Diefenbach M. Family-building decision aid and planning tool for young adult women after cancer treatment: protocol for preliminary testing of a web-based decision support intervention in a single-arm pilot study. BMJ Open. 2019 Dec 29;9(12):e033630. doi: 10.1136/bmjopen-2019-033630.

Reference Type DERIVED
PMID: 31888941 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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VAR0190

Identifier Type: OTHER

Identifier Source: secondary_id

IRB-52143

Identifier Type: OTHER

Identifier Source: secondary_id

K07CA229186

Identifier Type: NIH

Identifier Source: secondary_id

View Link

IRB-52143

Identifier Type: -

Identifier Source: org_study_id

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