BEFORE Decision Aid Implementation Study

NCT ID: NCT03629509

Last Updated: 2018-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

224 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-01

Study Completion Date

2019-12-31

Brief Summary

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Fertility is of great importance to young women with cancer. Concerns about the ability to become pregnant after cancer treatment may influence treatment decisions and fertility decision-making is challenging. Despite these challenges, there is a lack of fertility decision support tools. Our team developed the Begin Exploring Fertility Options, Risks and Expectations (BEFORE) decision aid for young breast cancer patients in Canada. This study aims to evaluate the implementation of the BEFORE decision aid in hospital settings through a stepped wedge cluster randomized trial.

Detailed Description

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The investigators will conduct a stepped wedge cluster randomized trial to sequentially implement the BEFORE decision aid in clinical settings that are currently recruiting young breast cancer patients for the Reducing the bUrden of Breast cancer in Young women (RUBY) Study (www.womensresearch.ca/ruby-study/).

For this trial 24 participating RUBY sites were grouped into 14 clusters (1 to 3 sites per cluster). The decision aid intervention will be sequentially rolled out over the course of 48 weeks to all clusters. None of the clusters will be switched from control to intervention during the first 6 weeks of the study to establish a baseline. Then two clusters will move from the control to the intervention every 6 weeks (called a 'step'). There will be 7 steps total during the study period. At the end of the 7th step all clusters (i.e., participating RUBY sites) will have received the decision aid intervention. The time-point of when the clusters will be switched from control to intervention will be randomized.

The data collection includes obtaining secondary data collected as part of the RUBY study from all patient participants who were enrolled in RUBY during the study period. The primary outcome is the number of patients reporting that fertility tools were recommended to them, based on RUBY participant responses to a 3-month fertility questionnaire. The investigators hypothesizes that following the implementation of the decision aid intervention a 20% difference will be observed, from 10% in the control to 30% in the intervention, in the number of patients who report that someone in their care team recommended a fertility tool.

Conditions

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Decision Support Techniques Breast Neoplasm Female Young Adult Evaluation Studies

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Stepped Wedge Cluster Randomized Trial
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Pre-Intervention

The BEFORE decision aid will be available for use on the RUBY communication portals (Twitter, Facebook and study portal)

Data will be collected 6 weeks before the implementation of the BEFORE decision aid in RUBY sites to establish a baseline

Group Type OTHER

BEFORE decision aid

Intervention Type BEHAVIORAL

Implementation of the BEFORE decision aid on RUBY communication portals

BEFORE Decision Aid Intervention

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1. We will advertise the availability of the BEFORE decision aid with posters placed in clinic areas at each RUBY site, and will have small handouts available to be distributed in clinic.
2. We will conduct an educational intervention describing and promoting the use of the BEFORE decision aid and general oncofertility information to nurses and support staff at each RUBY site. This will include an optional 1hr informational webinar, direct outreach and training of nurses/support staff on the use of the tool.

Group Type EXPERIMENTAL

BEFORE decision aid

Intervention Type BEHAVIORAL

Implementation of the BEFORE decision aid in clinical practice

Post-Intervention

Data will be collected after the BEFORE decision aid has been implemented in each RUBY site regarding the recommendation of fertility resources, most useful/least useful tool, and use of the BEFORE decision aid.

Group Type OTHER

BEFORE decision aid

Intervention Type BEHAVIORAL

Review impact of BEFORE decision aid implementation in clinical practice

Interventions

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BEFORE decision aid

Implementation of the BEFORE decision aid in clinical practice

Intervention Type BEHAVIORAL

BEFORE decision aid

Implementation of the BEFORE decision aid on RUBY communication portals

Intervention Type BEHAVIORAL

BEFORE decision aid

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Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Young females diagnosed with histologically-confirmed breast cancer will be eligible to participate if they:

1. are age =18 years and prior to their 41st birthday;
2. are able to provide verbal informed consent and complete the interviews in English or French;
3. completed the 3-month fertility questionnaire as part of the RUBY Study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Applied Health Research Centre

OTHER

Sponsor Role collaborator

Canadian Breast Cancer Foundation

OTHER

Sponsor Role collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

Sponsor Role collaborator

Unity Health Toronto

OTHER

Sponsor Role lead

Responsible Party

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Nancy Baxter

Chief of General Surgery, Scientist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nancy N Baxter, MD, FRCSC, FACS, PhD

Role: PRINCIPAL_INVESTIGATOR

Unity Health Toronto

Locations

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St. Michael's Hospital

Toronto, Ontario, Canada

Site Status

Countries

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Canada

Central Contacts

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Nancy N Baxter, MD, FRCSC, FACS, PhD

Role: CONTACT

416-864-6060 ext. 77021

Brittany Speller, MSc

Role: CONTACT

416-864-6060 ext. 77029

Facility Contacts

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Brittany, Speller

Role: primary

416-864-6060 ext. 77029

Other Identifiers

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17-361

Identifier Type: -

Identifier Source: org_study_id

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