Impact of Prisma on Donor Site Pain

NCT ID: NCT04050124

Last Updated: 2024-04-16

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-07

Study Completion Date

2021-11-29

Brief Summary

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The purpose of this study is to assess the feasibility of evaluating the use of a composite collagen, silver-oxidized regenerated cellulose matrix compared to the standard of care dressing on donor site pain for patients undergoing split-thickness skin grafting in preparation for a larger study.

Detailed Description

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Conditions

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Skin Graft Disorder Donor Site Complication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Promogran Prisma

Following standard of care split thickness skin grafting, patients randomized to the intervention group will receive Promogan Prisma as the primary contact dressing at the donor grafting site.

Group Type EXPERIMENTAL

Promogran Prisma

Intervention Type DEVICE

Promogran+SOC; composite collagen, silver-oxidized regenerated cellulose matrix

Standard of care (SOC) dressings

Intervention Type DEVICE

standard of care dressing on donor site pain for patients undergoing split-thickness skin grafting in preparation for a larger study.

Standard of care (SOC) dressings

Group Type ACTIVE_COMPARATOR

Standard of care (SOC) dressings

Intervention Type DEVICE

standard of care dressing on donor site pain for patients undergoing split-thickness skin grafting in preparation for a larger study.

Interventions

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Promogran Prisma

Promogran+SOC; composite collagen, silver-oxidized regenerated cellulose matrix

Intervention Type DEVICE

Standard of care (SOC) dressings

standard of care dressing on donor site pain for patients undergoing split-thickness skin grafting in preparation for a larger study.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient scheduled to undergo STSG for any reason
* Patient, or designated healthcare proxy, has read and signed the IRB-approved informed consent form.

Exclusion Criteria

* Active infection or history of radiation to the donor site
* Patient has a known sensitivity to Promogran Prisma™ or silver
* Elevated INR \>3.0
* Insensate at the donor site
* Chronic narcotic use (\>6 months of daily use)
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Scott Gorenstein, MD

Role: PRINCIPAL_INVESTIGATOR

NYU Langone Health

Locations

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NYU Langone Health

New York, New York, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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19-00437

Identifier Type: -

Identifier Source: org_study_id

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