A Study of a Low-Carbohydrate Diet to Improve Maternal Health After Childbirth

NCT ID: NCT04045353

Last Updated: 2023-04-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

11 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-12-20

Study Completion Date

2022-07-01

Brief Summary

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The study is evaluating the effects of a standard diet to a low carbohydrate diet in obese women after having a baby. The purpose of the study is to determine if a low carbohydrate diet is associated with improvement in insulin sensitivity in postpartum women.

Detailed Description

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Conditions

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Obesity Postpartum Weight Retention Insulin Sensitivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard of care

Subjects will receive standard counseling on obesity as part of routine postpartum care.

Group Type NO_INTERVENTION

No interventions assigned to this group

Low carbohydrate diet education

Subjects will receive educational materials regarding a low carbohydrate diet in addition to the standard counseling on obesity as part of routine postpartum care.

Group Type ACTIVE_COMPARATOR

Low carbohydrate diet education

Intervention Type BEHAVIORAL

A 200 page informational document that connects with an online application will be provided to subjects.

Low carbohydrate diet education with behavioral component

Subjects will receive in person instruction regarding a low carbohydrate diet as part of a 12 week course, in addition to receiving educational materials regarding a low carbohydrate diet and the standard counseling on obesity as part of routine postpartum care.

Group Type ACTIVE_COMPARATOR

Low carbohydrate diet education

Intervention Type BEHAVIORAL

A 200 page informational document that connects with an online application will be provided to subjects.

Low carbohydrate diet education with behavioral component

Intervention Type BEHAVIORAL

A 12 week course taught be a certified instructor will teach subjects about a low carbohydrate document. Subjects will also be given a 200 page informational document that connects with an online application.

Interventions

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Low carbohydrate diet education

A 200 page informational document that connects with an online application will be provided to subjects.

Intervention Type BEHAVIORAL

Low carbohydrate diet education with behavioral component

A 12 week course taught be a certified instructor will teach subjects about a low carbohydrate document. Subjects will also be given a 200 page informational document that connects with an online application.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Delivery at University of Texas Medical Branch
* Body max index greater than or equal to 30 kilograms/meters squared at the final prenatal visit prior to delivery.
* Singleton gestation.
* Accessibility to the internet.
* Basic understanding and comprehension of the English language to be assessed by study personnel at the time of recruitment.

Exclusion Criteria

* Diabetes mellitus on medication.
* Serious medical condition, such as heart failure, kidney failure, or severe asthma, as determined by the principle investigator.
* Planned pregnancy during study period.
* Enrolled in another trial that may affect outcome.
* Subject unlikely to be followed up after delivery.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Medical Branch, Galveston

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sara O Jacobs, MD

Role: PRINCIPAL_INVESTIGATOR

University of Texas

Antonio Saad, MD

Role: PRINCIPAL_INVESTIGATOR

University of Texas

Ashley Salazar, WHNP

Role: STUDY_DIRECTOR

University of Texas

Locations

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University of Texas Medical Branch

Galveston, Texas, United States

Site Status

Countries

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United States

References

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Morkrid K, Jenum AK, Sletner L, Vardal MH, Waage CW, Nakstad B, Vangen S, Birkeland KI. Failure to increase insulin secretory capacity during pregnancy-induced insulin resistance is associated with ethnicity and gestational diabetes. Eur J Endocrinol. 2012 Oct;167(4):579-88. doi: 10.1530/EJE-12-0452. Epub 2012 Aug 13.

Reference Type BACKGROUND
PMID: 22889687 (View on PubMed)

Rooney BL, Schauberger CW. Excess pregnancy weight gain and long-term obesity: one decade later. Obstet Gynecol. 2002 Aug;100(2):245-52. doi: 10.1016/s0029-7844(02)02125-7.

Reference Type BACKGROUND
PMID: 12151145 (View on PubMed)

Foster GD, Wyatt HR, Hill JO, McGuckin BG, Brill C, Mohammed BS, Szapary PO, Rader DJ, Edman JS, Klein S. A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med. 2003 May 22;348(21):2082-90. doi: 10.1056/NEJMoa022207.

Reference Type BACKGROUND
PMID: 12761365 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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18-0314

Identifier Type: -

Identifier Source: org_study_id

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