Effects of General Anesthesia on Quality of Recovery After Transaxillary Endoscopic Breast Augmentation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

104 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-07-28

Study Completion Date

2018-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Among aesthetic or cosmetic surgeries, breast augmentation was the most frequently performed and the endoscopic transaxillary approach has become the preferred incision for Asian women. As breast augmentation must be performed under general anesthesia accompanied by its effects and potential complications, types of general anesthesia may affect the quality of recovery. Currently, the two most common techniques of general anesthesia are inhalation anesthesia (IH) and total intravenous anesthesia (TIVA). The effects of these types of general anesthesia on the quality of recovery have been investigated for numerous surgical procedures. However, no prior studies have analyzed different types of anesthesia used for performing transaxillary endoscopic breast augmentation. This prospective, parallel, randomized controlled study will evaluate the effects of inhalation anesthesia vs. total intravenous anesthesia on the quality of recovery in patients undergoing transaxillary endoscopic breast augmentation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Difference Between Inhalation Anesthesia and Total Intravenous Anesthesia in Free Flap Surgery

NCT03263078

Surgery

COMPLETED NA

The Effect of Volatile Anesthesia and Total Intravenous Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Mastectomy and Breast Reconstruction Using Deep Inferior Epigastric Artery Perforator Free Flap

NCT05136508

Deep Inferior Epigastric Artery Perforator Flap Breast Reconstruction

COMPLETED NA

The Effects of General Anesthesia on Microcirculation of Central and Peripheral Soft Tissue: a Comparison of Inhalational and Intravenous Anesthetics

NCT02530632

Microcirculatory Effects of Anesthesia Inhalation and Intravenous Anesthesia

UNKNOWN NA

The Comparison of Oxidative Stress Between Inhalation Anesthetics

NCT00965445

Oxidative Stress Cardiac Surgery

COMPLETED

Retrospective Analysis of Anesthesia Procedure in Orthognathic Surgery

NCT05316545

Orthognathic Surgery

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Breast Augmentation Inhalation Anesthesia Total Intravenous Anesthesia Quality of Recovery

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

IH group

Inhalation anesthesia will be given during transaxillary endoscopic breast augmentation.

Group Type EXPERIMENTAL

Desflurane

Intervention Type DRUG

Anesthesia is maintained by desflurane in an oxygen air mixture of 60/40%. If inadequate depth of anesthesia is observed, the end-expiratory concentration of desflurane would be increased.

TIVA group

Total intravenous anesthesia will be given during transaxillary endoscopic breast augmentation.

Group Type ACTIVE_COMPARATOR

Propofol

Intervention Type DRUG

Anesthesia is maintained by propofol 100-200 μg/kg/min. If inadequate depth of anesthesia is observed, the rate of propofol infusion would be increased.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Desflurane

Anesthesia is maintained by desflurane in an oxygen air mixture of 60/40%. If inadequate depth of anesthesia is observed, the end-expiratory concentration of desflurane would be increased.

Intervention Type DRUG

Propofol

Anesthesia is maintained by propofol 100-200 μg/kg/min. If inadequate depth of anesthesia is observed, the rate of propofol infusion would be increased.

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients are appropriate for undergoing transaxillary endoscopic breast augmentation
* Age between 20-65 years
* Physical Status I or II as defined by the American Society of Anesthesiologists (ASA) Physical Status Classification System

Exclusion Criteria

* Having difficulty reading or hearing
* Diagnosed with addictive disorder
* Diagnosed with psychiatric disorder
* Physical Status III-VI as defined by the ASA Physical Status Classification System
* Presence of acute infection or inflammatory condition (e.g., fever).

Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No