SEARCH FOR OPTIMAL ANAESTHESIA IN RETROGRADE INTRARENAL SURGERY

NCT ID: NCT03999255

Last Updated: 2019-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

38 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-01

Study Completion Date

2018-05-01

Brief Summary

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Patients undergoing retrograde intrarenal surgery for kidney stones from November 2017 to May 2018 were prospectively recruited to participate in the study. In each case after the beginning of general anesthesia with mechanical ventilation surgeons were asked to assess the mobility of the operative field and conditions for laser lithotripsy according to the developed questionnaire scale. The questionnaire consisted of 5 degrees of assessment of kidney mobility and each question was scored from 1 to 5, 1 being very mobile (extremely poor conditions for dusting) and 5 completely immobile (Ideal conditions for dusting). After this assessment modified technique of general anesthesia was applied called combined respiratory support which consisted of reduction of tidal volume to 250-300 ml and respiratory rate to 4-5 per minute with transcatheter high frequency jet ventilation through endotracheal tube with a respiratory cycle frequency of 300 per minute and maintained during retrograde intrarenal surgery. At the beginning of combined respiratory approach, surgeons were once again asked to assess the mobility of the operative field and the conditions for laser lithotripsy. Main ventilation parameters were recorded and compared in both regimens.

Detailed Description

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Conditions

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Kidney Stone

Study Design

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Intervention Model

SEQUENTIAL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Patients undergoing intrarenal surgery

Group Type EXPERIMENTAL

combined respiratory support (CRS)

Intervention Type PROCEDURE

combined respiratory support (CRS) which consisted of reduction of tidal volume to 250-300 ml and respiratory rate to 4-5 per minute with transcatheter high-frequency jet ventilation (HFJV) through an endotracheal tube with a respiratory cycle frequency (RCF) of 300 per minute and maintained during RIRS.

Interventions

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combined respiratory support (CRS)

combined respiratory support (CRS) which consisted of reduction of tidal volume to 250-300 ml and respiratory rate to 4-5 per minute with transcatheter high-frequency jet ventilation (HFJV) through an endotracheal tube with a respiratory cycle frequency (RCF) of 300 per minute and maintained during RIRS.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Kidneys stones with indications for retrograde intrarenal surgery

Exclusion Criteria

* Patients with ASA class of greater than 3
* Patients with active urinary tract infection were excluded from the study
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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St. Petersburg State Pavlov Medical University

OTHER

Sponsor Role lead

Responsible Party

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nariman.gadjiev

Head of Endourology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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First Pavlov Saint Petersburg Universuty

Saint Petersburg, , Russia

Site Status

Countries

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Russia

References

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Gadzhiev N, Oibolatov U, Kolotilov L, Parvanyan S, Akopyan G, Petrov S, Cottone CM, Sung J, Okhunov Z. Reducing kidney motion: optimizing anesthesia and combining respiratory support for retrograde intrarenal surgery: a pilot study. BMC Urol. 2019 Jul 5;19(1):61. doi: 10.1186/s12894-019-0491-3.

Reference Type DERIVED
PMID: 31277626 (View on PubMed)

Other Identifiers

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№3/18

Identifier Type: -

Identifier Source: org_study_id

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