Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer Precursors
NCT ID: NCT03990025
Last Updated: 2024-02-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
90 participants
INTERVENTIONAL
2019-03-27
2020-10-17
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
DIAGNOSTIC
TRIPLE
Study Groups
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Linked Color Imaging - White Light Imaging
Participant undergoes gastroscopy via Linked Color Imaging first, then followed by White Light Imaging
Linked Color Imaging
Linked Color Imaging (LCI) is a form of image enhanced endoscopy that uses a laser endoscopic system that acquires images by simultaneously using narrow-band wavelength light and white light in an appropriate balance. This enhances slight color differences in the red region of the mucosa.
White Light Imaging
White Light Imaging (WLI) uses conventional white light that encompasses all bandwidths of light to illuminate areas of interest to obtain endoscopic images.
White Light Imaging - Linked Color Imaging
Participant undergoes gastroscopy via White Light Imaging first, then followed by Linked Color Imaging
Linked Color Imaging
Linked Color Imaging (LCI) is a form of image enhanced endoscopy that uses a laser endoscopic system that acquires images by simultaneously using narrow-band wavelength light and white light in an appropriate balance. This enhances slight color differences in the red region of the mucosa.
White Light Imaging
White Light Imaging (WLI) uses conventional white light that encompasses all bandwidths of light to illuminate areas of interest to obtain endoscopic images.
Interventions
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Linked Color Imaging
Linked Color Imaging (LCI) is a form of image enhanced endoscopy that uses a laser endoscopic system that acquires images by simultaneously using narrow-band wavelength light and white light in an appropriate balance. This enhances slight color differences in the red region of the mucosa.
White Light Imaging
White Light Imaging (WLI) uses conventional white light that encompasses all bandwidths of light to illuminate areas of interest to obtain endoscopic images.
Eligibility Criteria
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Inclusion Criteria
* Patients undergoing gastroscopy for symptom evaluation
* Patients undergoing gastroscopy for surveillance of known intestinal metaplasia
Exclusion Criteria
* Patients with previous surgical/endoscopic resection in stomach
* Patients with deranged coagulation and platelet function (INR\>1.5, Plt\<50)
* Patients with severe comorbid illness (ASA 3 and above)
50 Years
100 Years
ALL
No
Sponsors
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Singapore General Hospital
OTHER
Changi General Hospital
OTHER
Responsible Party
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Principal Investigators
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Tiing Leong Ang, MBBS
Role: PRINCIPAL_INVESTIGATOR
Changi General Hospital
Locations
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Singapore General Hospital
Singapore, , Singapore
Changi General Hospital
Singapore, , Singapore
Countries
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References
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Dohi O, Yagi N, Onozawa Y, Kimura-Tsuchiya R, Majima A, Kitaichi T, Horii Y, Suzuki K, Tomie A, Okayama T, Yoshida N, Kamada K, Katada K, Uchiyama K, Ishikawa T, Takagi T, Handa O, Konishi H, Naito Y, Itoh Y. Linked color imaging improves endoscopic diagnosis of active Helicobacter pylori infection. Endosc Int Open. 2016 Jul;4(7):E800-5. doi: 10.1055/s-0042-109049.
Paggi S, Mogavero G, Amato A, Rondonotti E, Andrealli A, Imperiali G, Lenoci N, Mandelli G, Terreni N, Conforti FS, Conte D, Spinzi G, Radaelli F. Linked color imaging reduces the miss rate of neoplastic lesions in the right colon: a randomized tandem colonoscopy study. Endoscopy. 2018 Apr;50(4):396-402. doi: 10.1055/a-0580-7405. Epub 2018 Mar 14.
Yao K. The endoscopic diagnosis of early gastric cancer. Ann Gastroenterol. 2013;26(1):11-22.
Sun X, Dong T, Bi Y, Min M, Shen W, Xu Y, Liu Y. Linked color imaging application for improving the endoscopic diagnosis accuracy: a pilot study. Sci Rep. 2016 Sep 19;6:33473. doi: 10.1038/srep33473.
Other Identifiers
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2018/2895
Identifier Type: -
Identifier Source: org_study_id
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