Management of Paroxystic Atrial Fibrillation in French Intensive Care Units

NCT ID: NCT03977883

Last Updated: 2021-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

742 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-05-13

Study Completion Date

2020-08-27

Brief Summary

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The primary purpose of the study is to evaluate treatment of new onset atrial fibrillation in french ICU.

Detailed Description

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Atrial fibrillation (AF) is a common arrhythmia in the ICU and is associated with significant morbidity. However, curative treatment remains unclearly established. In fact, there are no specific recommendations for new onset atrial fibrillation in ICU and only few studies have assessed this topic.

The PAF-ICU trial is an observational, prospective, multicenter, transversal trial. The main objective is to evaluate the management of paroxytic atrial fibrillation that occur in ICU.

The investigators want to document 2500 episodes of paroxystic atrial fibrillation in 50 ICU centers. In each center, the episodes are included consecutively until the required 50 episodes are obtained for each center.

A patient can present several episodes and each episode can be included in the study. A new episode is considered as such if it occurs more than one hour after the previous episode.

The follow-up period for each patient corresponds to the ICU stay.

Conditions

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New Onset Atrial Fibrillation ICU Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years
* Patient hospitalized in ICU
* New onset atrial fibrillation

Exclusion Criteria

* Age \< 18 years
* Parturient or breast-feeding woman
* Persistent or permanent atrial fibrillation
* Patients after cardiovascular or thoracic surgery
* Patients with therapeutic limitations
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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French Society of Anesthesia and Intensive Care Medecine

UNKNOWN

Sponsor Role collaborator

University Hospital, Clermont-Ferrand

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Michel Constantin

Role: STUDY_DIRECTOR

Réa Adulte CHU Clermont-Ferrand

Bernard Cosserant

Role: PRINCIPAL_INVESTIGATOR

Neuro-Réa CHU Clermont-Ferrand

Raiko Blondonnet

Role: PRINCIPAL_INVESTIGATOR

RMC CHU Clermont-Ferrand

Eric Kipnis

Role: PRINCIPAL_INVESTIGATOR

CHU Lille

Jonathan Paillot

Role: PRINCIPAL_INVESTIGATOR

CHU Besancçon

Charles Vidal

Role: PRINCIPAL_INVESTIGATOR

CHU de la Réunion

Laurent Muller

Role: PRINCIPAL_INVESTIGATOR

CHU Nimes

Johann Auchabie

Role: PRINCIPAL_INVESTIGATOR

CH Cholet

Guillaume Grillet

Role: PRINCIPAL_INVESTIGATOR

CH Lorient

Philippe Seguin

Role: PRINCIPAL_INVESTIGATOR

CHU Rennes

Philippe Guerci

Role: PRINCIPAL_INVESTIGATOR

CHRU Nancy

Bernard Lalanne

Role: PRINCIPAL_INVESTIGATOR

Hôpital Saint-Joseph - Marseille

Marc Leone

Role: PRINCIPAL_INVESTIGATOR

Hôpital Nord - APHM

Stanislas Ledochowski

Role: PRINCIPAL_INVESTIGATOR

CH Bourgoin-Jallieu

Matthieu Legrand

Role: PRINCIPAL_INVESTIGATOR

Hôpital Saint-Louis - APHP

Jeremy Bourenne

Role: PRINCIPAL_INVESTIGATOR

La Timone APHM

Michel Durand

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Grenoble

Antoine Monsel

Role: PRINCIPAL_INVESTIGATOR

La Pitié Sapêtrière

Mathieu Guilbart

Role: PRINCIPAL_INVESTIGATOR

CHU Amiens

Matthieu Biais

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Bordeaux

Cédric Bruel

Role: PRINCIPAL_INVESTIGATOR

CH Saint-Joseph Paris

Antoine Roquilly

Role: PRINCIPAL_INVESTIGATOR

Nantes University Hospital

Gaëtan Plantefeve

Role: PRINCIPAL_INVESTIGATOR

CH Argenteuil

Jérôme Morel

Role: PRINCIPAL_INVESTIGATOR

CHU SAINT-ETIENNE

Carole Ichai

Role: PRINCIPAL_INVESTIGATOR

CHU NICE

Adrien Auvet

Role: PRINCIPAL_INVESTIGATOR

CH Dax

Enora Atchade

Role: PRINCIPAL_INVESTIGATOR

Hôpital Bichat

Sigismond Lasocki

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Angers

Pierre-Eric Danin

Role: PRINCIPAL_INVESTIGATOR

Clinique Les Sources Nice

Marc Danguy Des Deserts

Role: PRINCIPAL_INVESTIGATOR

Hôpital d'Instruction des Armées de Brest

Evelina Ochin Salatova

Role: PRINCIPAL_INVESTIGATOR

Hôpital Simone Veil - CH d'Eaubonne

Antoine Rouget

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Toulouse

Armand Mekontso Dessap

Role: PRINCIPAL_INVESTIGATOR

Hôpital Henri Mondor APHP

Justine Perrot

Role: PRINCIPAL_INVESTIGATOR

CHU Dijon

Jibba Amraoui

Role: PRINCIPAL_INVESTIGATOR

Institut Régional du Cancer de Montpellier

Matthias Garot

Role: PRINCIPAL_INVESTIGATOR

CHU Lille

Locations

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CHU

Amiens, , France

Site Status

CHU

Angers, , France

Site Status

CH

Argenteuil, , France

Site Status

CHU

Besançon, , France

Site Status

CHU

Bordeau, , France

Site Status

CH

Bourgoin, , France

Site Status

Hôpital d'Instruction des Armées

Brest, , France

Site Status

CH

Cholet, , France

Site Status

CHU

Clermont-Ferrand, , France

Site Status

CH

Dax, , France

Site Status

CHU

Dijon, , France

Site Status

CH

Eaubonne, , France

Site Status

CHU

Grenoble, , France

Site Status

CHU

Lille, , France

Site Status

Hôpital du Scorff

Lorient, , France

Site Status

APHM

Marseille, , France

Site Status

Hôpital Saint-Joseph

Marseille, , France

Site Status

La Timone APHM

Marseille, , France

Site Status

Institut Régional du Cancer de Montpellier

Montpellier, , France

Site Status

CHU

Nancy, , France

Site Status

CHU

Nantes, , France

Site Status

CHU

Nice, , France

Site Status

Clinique médicale les Sources

Nice, , France

Site Status

CHU

Nîmes, , France

Site Status

Groupe Hospitalier Saint Joseph

Paris, , France

Site Status

Hôpital Bichat

Paris, , France

Site Status

Hôpital Henri Mondor

Paris, , France

Site Status

Hôpital La Pitié Salpêtrière

Paris, , France

Site Status

Hôpital Saint-Louis

Paris, , France

Site Status

CHU

Rennes, , France

Site Status

CHU

Saint-Etienne, , France

Site Status

CHU

Toulouse, , France

Site Status

Countries

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France

References

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Pardo E, Futier E, Muller L, Besch G, Vardon-Bounes F, Kipnis E, Lasocki S, Ledochowski S, Ochin E, Bourenne J, Grillet G, Auvet A, Mekontso Dessap A, Bruel C, Launey Y, Fiorillo M, Jabaudon M, Godet T, Mulliez A, Constantin JM; SFAR Research Network. Management of new-onset atrial fibrillation in critically ill patients: A national multicenter prospective cohort. Anaesth Crit Care Pain Med. 2025 Sep 26;45(1):101617. doi: 10.1016/j.accpm.2025.101617. Online ahead of print.

Reference Type DERIVED
PMID: 41016469 (View on PubMed)

Other Identifiers

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PAF-ICU - RNI 2018 CONSTANTIN

Identifier Type: -

Identifier Source: org_study_id

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