Time From Onset of Fever to Administration of Antibiotics in Neutropenic Fever Patients

NCT ID: NCT03968328

Last Updated: 2023-07-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

315 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-06-19

Study Completion Date

2023-01-17

Brief Summary

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This trial uses an interview and a survey to gather information from cancer patients about the onset of their fever and the administration of antibiotics. Collecting information from patients may help doctors to assess the relationship between time to antibiotic administration and inhospital cause specific death, intensive care unit admission, hospital length of stay, and positive blood cultures.

Detailed Description

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PRIMARY OBJECTIVES:

I. To assess the prognostic value of the length of time between the time onset of fever and first antibiotic administration on cause specific 14 day mortality rate.

SECONDARY OBJECTIVES:

I. To assess the associations of the length of time between the time onset of fever and first antibiotic administration with intensive care unit (ICU) admission, ICU length of stay, length of hospitalization and percentage of patients with positive blood cultures.

OUTLINE:

Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.

Conditions

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Febrile Neutropenia Fever

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational (interview, survey)

Patients respond to a survey and participate in an interview with study staff about their fever and when they started feeling unwell.

Interview

Intervention Type OTHER

Take part in interview

Survey Administration

Intervention Type OTHER

Respond to survey

Interventions

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Interview

Take part in interview

Intervention Type OTHER

Survey Administration

Respond to survey

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

--\> 18 years of age

* Temperature above 38.0 documented
* ANC\< 500/mm3

Exclusion Criteria

--Age \<18
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

M.D. Anderson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sai-ching Yeung, MD

Role: PRINCIPAL_INVESTIGATOR

M.D. Anderson Cancer Center

Locations

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M D Anderson Cancer Center

Houston, Texas, United States

Site Status

Countries

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United States

Related Links

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http://www.mdanderson.org

MD Anderson Cancer Center

Other Identifiers

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NCI-2019-02655

Identifier Type: REGISTRY

Identifier Source: secondary_id

2015-0272

Identifier Type: OTHER

Identifier Source: secondary_id

2015-0272

Identifier Type: -

Identifier Source: org_study_id

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