Comparison of Lysine Clonixinate, Ketorolac and Metamizole Sodium in Scorpion Stings
NCT ID: NCT03943199
Last Updated: 2019-07-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
160 participants
INTERVENTIONAL
2019-05-05
2019-07-20
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Comparative Efficacy of Lidocaine Spray Versus Vaginal Dinoprostone in IUD Insertion
NCT04339361
TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone
NCT03028012
Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement
NCT05875571
Effective Treatments for Jellyfish Stings
NCT02015195
Intravenous Lidocaine Versus Morphine for Severe Pain in the ED
NCT02912195
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Due to the high affinity on ion channels, where a cystine inhibitor BmP01, it is directed to the nociceptive ion channel TRPV1 to produce pain.Pain has been reported to occur in approximately 97% of patients They are seen in the emergency room.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
SEQUENTIAL
TREATMENT
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Metamizole sodium
1 gram intravenous, will be diluted in 0.9% physiological solution of 100 ml, applied for 30 minutes
Visual Analogue Scale for pain
Will be assessed at 0´, 30´, 60´, 90 minutes and 18 hours after the application of the analgesic.
Ketorolac
60 milligrams intravenously, it will be added to 20 ml with 0.9% physiological solution, it will be applied for 5 minutes
Visual Analogue Scale for pain
Will be assessed at 0´, 30´, 60´, 90 minutes and 18 hours after the application of the analgesic.
Lysine Clonixinate
100 milligram intravenously, diluted in 5% glucose solution of 100 ml, applied for 30 minutes
Visual Analogue Scale for pain
Will be assessed at 0´, 30´, 60´, 90 minutes and 18 hours after the application of the analgesic.
Placebo
20 milliliters of 0.9% physiological solution, will be applied for 5 minutes.
Visual Analogue Scale for pain
Will be assessed at 0´, 30´, 60´, 90 minutes and 18 hours after the application of the analgesic.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Visual Analogue Scale for pain
Will be assessed at 0´, 30´, 60´, 90 minutes and 18 hours after the application of the analgesic.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Patients\> 18 years old
* Clinical diagnosis of scorpion sting poisoning grade I, II and III.
* Chronic degenerative diseases (renal failure, hypertension, liver damage)
Exclusion Criteria
* Patients who are transferred to a unit of second level of care.
* Patients with pharmacological treatment prior
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Instituto Bioclon S.A. de C.V.
INDUSTRY
Mexican Red Cross
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Josue Saul Almaraz Lira
Principal Investigator
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Alfredo Luis H Chávez Haro
Role: STUDY_DIRECTOR
Investigator
Josue Saul H Almaraz
Role: PRINCIPAL_INVESTIGATOR
Investigator
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Cruz Roja Mexicana, Delegación León
León, Guanajuato, Mexico
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
CRM-Alacran-2019
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.