Effectiveness of a Novel Workplace-based Exercise Intervention: a Pilot Study

NCT ID: NCT03941145

Last Updated: 2020-03-24

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 23 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-05-01
• Study Completion Date: 2019-11-13

Brief Summary

Sufficient physical activity and a good cardiorespiratory fitness level (CRF) are central in cardiovascular disease (CVD) risk reduction. However, many people remain inactive, partly because current exercise recommendations fail to address important barriers to exercise. A novel exercise protocol has previously been developed called 'reduced-exertion high-intensity interval training' (REHIT), which can remove several common perceived barriers to exercise. REHIT 1) improves CRF and other key CVD risk factors, 2) is genuinely time-efficient (total time-commitment of just 2x10 min per week), 3) is well-tolerated, manageable, and not associated with negative affective responses, and 4) can be done in the workplace, in work-clothes and without a need to shower afterwards. To date, this intervention has only been investigated in a lab-setting. Therefore, in the present randomised controlled trial, the 'real-world' effectiveness of REHIT in improving maximal aerobic capacity (V̇O2max; a key risk factors of CVD) will be investigated in a workplace setting. Participants' attitudes and psychological responses to REHIT will be assessed to evaluate the likelihood of successful implementation. In 2 study centres, a total of up to n=50 physically inactive male and female office workers will be recruited to perform 6 weeks of unsupervised, computer-guided, office-based REHIT (n=25) or act as a control (n=25).

Conditions

Health Behavior

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Exercise

Participants allocated to the intervention group will be asked to perform 2 exercise sessions per week for 6 weeks. Each session will involve 10 min of low-intensity cycling (25 W) interspersed with two 20-s 'all-out' cycle sprints against a resistance equivalent to 5% of body mass. The exercise intervention will be delivered on a commercially available cycle ergometer with software developed by CAR.O.L.

Group Type: EXPERIMENTAL

Reduced-Exertion High-Intensity Interval Training (REHIT)

Intervention Type: BEHAVIORAL

REHIT is a type of Sprint Interval Training (SIT) that has been shown to be efficacious at improving maximal aerobic capacity using a minimal volume of exercise.

Control

The effects of the intervention will be compared to a no-intervention control group recruited from the same workplace settings.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Reduced-Exertion High-Intensity Interval Training (REHIT)

REHIT is a type of Sprint Interval Training (SIT) that has been shown to be efficacious at improving maximal aerobic capacity using a minimal volume of exercise.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Employee at participating workplace

Exclusion Criteria

• Aged < 18 years or > 60 years
• History of type 2 diabetes
• Insulin therapy
• Use of β-blockers
• Use of inhaled steroids (e.g. for asthma)
• Any cardiovascular condition with the exception of well-controlled uncomplicated hypertension (systolic >140 mm Hg and/or >90 mm Hg after at least 5 minutes of seated rest), which is treated with no more than two drugs (either an ACE, ARB, calcium channel blocker, or diuretic)
• Cerebrovascular disease including previous stroke or aneurysm
• History of exercise-induced asthma
• History of type 1 diabetes mellitus or a history of ketoacidosis
• History of other specific types of diabetes (e.g., genetic syndromes, secondary pancreatic diabetes, diabetes due to endocrinopathies, drug or chemical-induced, and post organ transplant)
• History of respiratory disease including pulmonary hypertension or chronic obstructive pulmonary disease
• History of musculoskeletal or neurological disorders
• Active inflammatory bowel disease
• History of renal disease
• Other metabolic diseases, including hyper/ hypo-parathyroidism, hyper/hypo-thyroidism, and Cushing's disease.
• BMI>35 kg/m2
• A clinically significant resting ECG abnormality at the pre-screening visit which in the opinion of the cardiologist exposes the participant to risk by take part in the main trial.
• 'Yes' to any questions on a standard physical activity readiness questionnaire (PARQ)
• Classification as moderately or highly physically active on the International Physical Activity Questionnaire (IPAQ)
• Current participation in another research study
• Inability to fully understand the verbal and written descriptions of the study in English, and the instructions provided during the study

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Swansea University

OTHER

Sponsor Role: collaborator

University of Stirling

OTHER

Sponsor Role: lead

Responsible Party

Niels Vollaard

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Stirling Council

Stirling, , United Kingdom

Countries

United Kingdom

References

Metcalfe RS, Atef H, Mackintosh K, McNarry M, Ryde G, Hill DM, Vollaard NBJ. Time-efficient and computer-guided sprint interval exercise training for improving health in the workplace: a randomised mixed-methods feasibility study in office-based employees. BMC Public Health. 2020 Mar 12;20(1):313. doi: 10.1186/s12889-020-8444-z.

Reference Type: DERIVED

PMID: 32164631 (View on PubMed)

Other Identifiers

18/19 036

Identifier Type: -

Identifier Source: org_study_id