Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
120 participants
OBSERVATIONAL
2019-01-03
2022-02-03
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Surgical intervention for non-union
The investigation group will consist of cases undergoing surgical intervention for non-union
Next-generation sequencing of swabs collected during surgery
Traditional swabs for culturing as well as swabs for NGS testing will be collected
Acute fracture fixation
The control group will consist of cases undergoing acute fracture fixation
Next-generation sequencing of swabs collected during surgery
Traditional swabs for culturing as well as swabs for NGS testing will be collected
Interventions
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Next-generation sequencing of swabs collected during surgery
Traditional swabs for culturing as well as swabs for NGS testing will be collected
Eligibility Criteria
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Inclusion Criteria
3. Presumed Septic and Aseptic nonunions
4. \>18 years old and able to provide informed consent
Exclusion Criteria
1. Pathological fractures at index injury
2. Patients on antibiotic therapy \<2 weeks prior to surgery
Inclusion:
1. Patients undergoing surgical intervention for nonunion following a traumatic closed long bone fractures (femur shaft, tibia, humerus)
2. \>18 years old and able to provide informed consent
Exclusion:
1. Pathological fractures at index injury
2. Patients on antibiotic therapy \<2 weeks prior to surgery
18 Years
ALL
No
Sponsors
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Rothman Institute Orthopaedics
OTHER
Responsible Party
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Locations
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Rothman Institute
Philadelphia, Pennsylvania, United States
Countries
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Other Identifiers
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Krieg2019
Identifier Type: -
Identifier Source: org_study_id
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