Safety and Electrical Performances of XFINE Leads

NCT ID: NCT03922386

Last Updated: 2023-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

188 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-09-09

Study Completion Date

2021-07-23

Brief Summary

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The purpose of the study is to confirm the safety and the electrical performances of the XFINE passive pacing leads, for both right ventricular (RV) straight models and right atrial (RA) J-shape models, up to 12 months follow-up post implant.

Detailed Description

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All subjects will be followed until 12 months follow-up post implant.

At each follow-up visits (3, 6 and 12 months), electrical performances will be measured and safety will be monitored during the whole study duration.

Conditions

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Bradycardia

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Post market, multicenter, international, prospective, open label, two arms and longitudinal non comparative non randomized study.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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JX model

Subjects implanted with an RA XFINE lead (JX model)

Group Type OTHER

XFINE leads

Intervention Type DEVICE

Pacemaker subjects with at least one XFINE passive lead

TX model

Subjects implanted with an RV XFINE lead (TX model)

Group Type OTHER

XFINE leads

Intervention Type DEVICE

Pacemaker subjects with at least one XFINE passive lead

Interventions

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XFINE leads

Pacemaker subjects with at least one XFINE passive lead

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Any subject newly implanted according to the most recent guidelines from the European Society of Cardiology (ESC) for less than10 days with:

* a Single Chamber (SR) or a Dual Chamber (DR) pacemaker from Microport CRM S.r.l.
* any right atrial and/or right ventricular XFINE lead
2. Have reviewed, signed and dated the informed consent

Exclusion Criteria

1. Included in another clinical study that could confound the results of this study such as studies involving intra-cardiac device
2. Contraindication to a maximum single dose of 310 µg Dexamethasone Sodium Phosphate (DSP)
3. Tricuspid valvular disease or tricuspid replacement heart valve (mechanical or tissue) only for subject with DR pacemaker
4. Active myocarditis, pocket and/or lead infection
5. Age less than 18 years old or under guardianship or kept in detention
6. Life expectancy less than 1 year
7. Known pregnancy, women breastfeeding or in childbearing age without an adequate contraceptive method
8. Be unavailable for the scheduled follow-up associated with this clinical study or refusal to cooperate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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MicroPort CRM

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alfredo Bardají, Dr.

Role: PRINCIPAL_INVESTIGATOR

Hospital Universitari Joan XXIII, Tarragona, Spain

Locations

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Centre Hospitalier de Cahors

Cahors, , France

Site Status

CHU de Clermont-Ferrand

Clermont-Ferrand, , France

Site Status

Hôpital de la Croix-Rousse

Lyon, , France

Site Status

Clinica Medica - Azienda Ospedaliero Universitaria Careggi

Florence, , Italy

Site Status

Ospedale Santa Maria Nuova

Florence, , Italy

Site Status

Clinica San Carlo

Milan, , Italy

Site Status

Azienda Ospedaliera Santa Maria degli Angeli

Pordenone, , Italy

Site Status

Ospedale Policlinico Casilino

Roma, , Italy

Site Status

Ospedale Civile di Vigevano

Vigevano, , Italy

Site Status

Ospedale Civile di Voghera

Voghera, , Italy

Site Status

Centro Hospitalar do Baixo Vouga, E.P.E.

Aveiro, , Portugal

Site Status

Centro Hospitalar do Alto Ave - Hospital da Senhora da Oliveira

Creixomil, , Portugal

Site Status

Centro Hospitalar de Leiria - Hospital de Santo André

Leiria, , Portugal

Site Status

Centro Hospitalar Vila Nova de Gaia/Espinho

Vila Nova de Gaia, , Portugal

Site Status

Hospital Universitari Joan XXIII

Tarragona, , Spain

Site Status

Hospital Doctor Peset

Valencia, , Spain

Site Status

Leeds Teaching Hospitals NHS Trust - Leeds General Infirmary

Leeds, , United Kingdom

Site Status

Kingston Hospital

London, , United Kingdom

Site Status

Lister Hospital

Stevenage, , United Kingdom

Site Status

Countries

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France Italy Portugal Spain United Kingdom

Other Identifiers

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LBFX05 - PERSEPOLIS

Identifier Type: -

Identifier Source: org_study_id

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