Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery
NCT ID: NCT03919786
Last Updated: 2019-12-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
150 participants
INTERVENTIONAL
2019-04-01
2020-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
QUADRUPLE
Study Groups
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intervention group
Durg：0.375% Ropivacaine and 1% lidocaine
topical local anesthesia of pulmonary vein with lidocaine+ropivacaine at the beginning and the end of surgery operation.
Block vagus nerve with lidocaine+ropivacaine 1ml after exposing the pleural apex
topical local anesthesia of pulmonary vein combined with vagus nerve block
Injecting 1% lidocaine 1.5ml+0.375% ropivacaine 1.5ml into vascular sheaths of all pulmonary vein of the surgery side at the beginning of surgery operation.
Wrapping all pulmonary vein of the surgery side with cotton sheet infiltrated with 1% lidocaine+0.375% ropivacaine at the end of surgery operation.
Blocking vagus nerve above the aortic vein on the right side of the trachea with 1% lidocaine 1ml+0.375% ropivacaine 1ml after exposing the pleural apex.
normal saline group
Same volume of normal saline will be administrated
topical local anesthesia of pulmonary vein combined with vagus nerve block
Injecting 1% lidocaine 1.5ml+0.375% ropivacaine 1.5ml into vascular sheaths of all pulmonary vein of the surgery side at the beginning of surgery operation.
Wrapping all pulmonary vein of the surgery side with cotton sheet infiltrated with 1% lidocaine+0.375% ropivacaine at the end of surgery operation.
Blocking vagus nerve above the aortic vein on the right side of the trachea with 1% lidocaine 1ml+0.375% ropivacaine 1ml after exposing the pleural apex.
Interventions
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topical local anesthesia of pulmonary vein combined with vagus nerve block
Injecting 1% lidocaine 1.5ml+0.375% ropivacaine 1.5ml into vascular sheaths of all pulmonary vein of the surgery side at the beginning of surgery operation.
Wrapping all pulmonary vein of the surgery side with cotton sheet infiltrated with 1% lidocaine+0.375% ropivacaine at the end of surgery operation.
Blocking vagus nerve above the aortic vein on the right side of the trachea with 1% lidocaine 1ml+0.375% ropivacaine 1ml after exposing the pleural apex.
Eligibility Criteria
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Inclusion Criteria
* ASA class I-III
* Age is greater than or equal to 50 years old
* Han Nationality, mother tongue is chinese
* The people signed informed consent
Exclusion Criteria
* sick sinus syndrome
* history of second-degree atrioventricular block
* taking class I or class III antiarrhythmic drugs or β-receptor blocker
* history of radiofrequency ablation
* hyperthyroidism
* contraindications of ropivacaine, lidocaine
* pregnancy and lactation
50 Years
ALL
No
Sponsors
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Han Yuan
OTHER
Responsible Party
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Han Yuan
Doctor-in-charge of Anesthetist
Locations
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Department of Anesthesiology of the Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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XYFY2019-KL002-02
Identifier Type: -
Identifier Source: org_study_id
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