Prostate Cancer in Firemen: Early Diagnosis Because of Increased Diagnostic Pressure?

NCT ID: NCT03896178

Last Updated: 2021-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

137536 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-01

Study Completion Date

2020-02-02

Brief Summary

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Firefighters, police, military personnel and pilots are all shown to have a higher incidence of prostate cancer than the general population. A possible explanation for this is that these four groups of employees need regular mandatory health-checkups. If these checkups increase the chances of having a PSA or DRE performed one could expect the workers in question to have a higher probability than the general population of being diagnosed with prostate cancer. If this is the case the four groups should have cancers that are lower grade and have better survival. The investigators wish to examine this by comparing the four groups with a control group made up of all other workers with regards to prognostic factors at the time of diagnosis and survival rates. This will be done by extracting data from the Cancer Registry of Norway, coupled with employment data from Statistics Norway. This study is also a part of a project on cancer in firefighters. If the prostate cancers in firefighters differ significantly from the other three specified groups, this could point to an exposure specific for firefighters, e.g. fire smoke, as an etiologic factor.

Detailed Description

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Conditions

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Prostate Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

OTHER

Study Groups

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Firefighters

None, observational study

Intervention Type OTHER

None, observational study

Pilots

None, observational study

Intervention Type OTHER

None, observational study

Police

None, observational study

Intervention Type OTHER

None, observational study

Military personnel

None, observational study

Intervention Type OTHER

None, observational study

Controls

Control group matched for geographic location (county), and year of diagnosis. Consisting of all other workers than the four specified groups.

None, observational study

Intervention Type OTHER

None, observational study

Interventions

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None, observational study

None, observational study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All cases of prostate cancer as registered by the Cancer Registry of Norway

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Norwegian Institute of Public Health

OTHER_GOV

Sponsor Role collaborator

Extrastiftelsen

OTHER

Sponsor Role collaborator

The National Institute of Occupational Health

UNKNOWN

Sponsor Role collaborator

Norwegian Confederation of Trade Unions

UNKNOWN

Sponsor Role collaborator

Fagforbundet

UNKNOWN

Sponsor Role collaborator

Gjensidige Foundation

UNKNOWN

Sponsor Role collaborator

Norwegian Cancer Society

OTHER

Sponsor Role collaborator

Norwegian Firefighters Fight Cancer

UNKNOWN

Sponsor Role collaborator

Norwegian Labour Inspection Authority

UNKNOWN

Sponsor Role collaborator

Oslo University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jarle Jakobsen

PhD-student

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cancer Registry of Norway

Oslo, , Norway

Site Status

Countries

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Norway

Other Identifiers

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2019/542

Identifier Type: -

Identifier Source: org_study_id

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