Genetic and Phenotypic Characteristics of Mitral Valve Prolapse
NCT ID: NCT03884426
Last Updated: 2021-08-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
1000 participants
OBSERVATIONAL
2010-12-31
2021-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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FAMILY_BASED
PROSPECTIVE
Study Groups
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Patients with MVP
The patients concerned are patients with known or recently discovered Barlow-type mitral prolapse, whatever the degree of severity.
No interventions assigned to this group
Normal relatives
Related healthy patients, for an average of 6 individuals per family
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* with typical mitral valve prolapse
* relatives examined during familial screening
Exclusion Criteria
ALL
Yes
Sponsors
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University Hospital, Brest
OTHER
Rennes University Hospital
OTHER
Nantes University Hospital
OTHER
Responsible Party
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Principal Investigators
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Vincent Probst, PU-PH
Role: PRINCIPAL_INVESTIGATOR
Nantes University Hospital
Hervé Le Marec, PU-PH
Role: PRINCIPAL_INVESTIGATOR
Nantes University Hospital
Jean-Jacques Schott, DR
Role: PRINCIPAL_INVESTIGATOR
Institut National de la Santé Et de la Recherche Médicale, France
Locations
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Brest University Hospital
Brest, , France
Nantes University Hospital
Nantes, , France
Rennes University Hospital
Rennes, , France
Countries
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Central Contacts
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Facility Contacts
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References
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Huttin O, Girerd N, Jobbe-Duval A, Constant Dit Beaufils AL, Senage T, Filippetti L, Cueff C, Duarte K, Fraix A, Piriou N, Mandry D, Pace N, Le Scouarnec S, Capoulade R, Echivard M, Sellal JM, Marrec M, Beaumont M, Hossu G, Trochu JN, Sadoul N, Marie PY, Guenancia C, Schott JJ, Roussel JC, Serfaty JM, Selton-Suty C, Le Tourneau T. Machine Learning-Based Phenogrouping in MVP Identifies Profiles Associated With Myocardial Fibrosis and Cardiovascular Events. JACC Cardiovasc Imaging. 2023 Oct;16(10):1271-1284. doi: 10.1016/j.jcmg.2023.03.009. Epub 2023 May 17.
Other Identifiers
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RC12_0143
Identifier Type: -
Identifier Source: org_study_id
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