Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity

NCT ID: NCT03860441

Last Updated: 2019-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

77 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-07-01

Study Completion Date

2018-09-30

Brief Summary

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Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group. The investigators tested close (battery of cognitive functions) and far transfer (postural and mobility control, EEG, blood samples) of the CCT. Additionally, the investigators were interested into seeing a long-lasting effect, therefore participants were brought back to the laboratory 1 year post CCT.

Detailed Description

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Conditions

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Cognitive Decline Cognitive Impairment Aging Motor Coordination or Function

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants in the intervention group followed a computerized cognitive training program for 2-months, 3x/week, 40min/session
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
A single-blind randomized controlled trial

Study Groups

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Intervention group

Participants in the intervention group received 24 sessions of computerized cognitive training, with a total time of 960 min.

Group Type EXPERIMENTAL

Computerized cognitive training

Intervention Type OTHER

Intervention used CogniFit platform with Personalized brain training sub-option

Active control group

Participants in the control group attended activities separate activities, such as learning about healthy lifestyle, had cooking and other social lessons for the same amount as the intervention group performed cognitive training.

Group Type ACTIVE_COMPARATOR

Computerized cognitive training

Intervention Type OTHER

Intervention used CogniFit platform with Personalized brain training sub-option

Interventions

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Computerized cognitive training

Intervention used CogniFit platform with Personalized brain training sub-option

Intervention Type OTHER

Other Intervention Names

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cognitive remediation cognitive training

Eligibility Criteria

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Inclusion Criteria

* active and healthy older adults with no major health issues
* members of the Center for Daily Activity Koper (Slovenia)
* had normal or corrected-to-normal vision;
* reported no history of cardiovascular, neurological, or psychiatric conditions

Exclusion Criteria

* younger than 60
* smoking; regular alcohol consumption;
* acute or chronic skeletal, neuromuscular, metabolic and cardiovascular disease condition;
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Primorska

OTHER

Sponsor Role collaborator

Albert Einstein College of Medicine

OTHER

Sponsor Role collaborator

Vrije Universiteit Brussel

OTHER

Sponsor Role collaborator

Science and Research Centre Koper

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Center for Daily Activity Koper (Slovenia)

Koper, , Slovenia

Site Status

Countries

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Slovenia

References

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Marusic U, Kavcic V, Giordani B, Gerzevic M, Meeusen R, Pisot R. Computerized spatial navigation training during 14 days of bed rest in healthy older adult men: Effect on gait performance. Psychol Aging. 2015 Jun;30(2):334-340. doi: 10.1037/pag0000021. Epub 2015 May 4.

Reference Type BACKGROUND
PMID: 25938245 (View on PubMed)

Verghese J, Mahoney J, Ambrose AF, Wang C, Holtzer R. Effect of cognitive remediation on gait in sedentary seniors. J Gerontol A Biol Sci Med Sci. 2010 Dec;65(12):1338-43. doi: 10.1093/gerona/glq127. Epub 2010 Jul 19.

Reference Type RESULT
PMID: 20643703 (View on PubMed)

Marusic U, Verghese J, Mahoney JR. Cognitive-Based Interventions to Improve Mobility: A Systematic Review and Meta-analysis. J Am Med Dir Assoc. 2018 Jun;19(6):484-491.e3. doi: 10.1016/j.jamda.2018.02.002. Epub 2018 Apr 19.

Reference Type RESULT
PMID: 29680203 (View on PubMed)

Other Identifiers

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GIBKOP2017

Identifier Type: -

Identifier Source: org_study_id

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