Factors Affecting the Pulpal Prognosis of Injured Teeth

NCT ID: NCT03845426

Last Updated: 2020-06-04

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 25 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-02-25
• Study Completion Date: 2020-03-01

Brief Summary

Factors affecting the pulpal prognosis of injured teeth. Dental injuries may affect the survival of teeth. It is recommended to monitor the injured teeth at regular intervals to ensure that the appropriate treatment is delivered promptly. In order to conclude what treatment is required, a correct diagnosis must be reached.

However, reaching this diagnosis can be difficult as injured teeth often respond erroneously to many of the diagnostic tests used, thereby affecting our ability to interpret the results.

This study aims to identify the clinical factors that affect the ability of the blood supply of a tooth to survive an injury. This will help ensure that patients are provided with the appropriate treatment with the avoidance of delays that may affect the long-term survival of the tooth.

Patients that attend the Edinburgh Dental Institute trauma clinic will be invited to participate in this study. The patients, seen on this clinic, are assessed in regular intervals in a systematic way, as per accepted and validated international guidelines on the subject of dental trauma. There are specific investigations and clinical assessments that are carried out on the initial and each review appointment.

The study will attempt to identify those teeth that lose their vitality at different points following the injury and will attempt to link this to the nature of the injury suffered. The data will be collected from the patients' routine dental trauma assessment and no additional investigations will be required. As per routine practice the patients are reviewed for one year following their injury unless otherwise indicated. All responses to the investigations will be collected and combined to identify the prognostic factors associated with the loss of vitality of traumatised teeth.

Detailed Description

Dento-alveolar trauma may affect the quality of life of patients and the long term prognosis of the teeth. Following dental trauma regular monitoring and follow up of the teeth is required to ensure that the appropriate treatment is delivered promptly. Although there is information in the literature focused on child and adolescent dental trauma, there is limited information regarding traumatised permanent teeth. Permanent teeth have differing healing capacity after injury and this is dependent on the degree of root formation.

During the initial assessment of patients that have suffered from dental trauma, negative responses to investigations assessing the health of the vasculature might lead clinicians to initiate unnecessary and irreversible treatment on traumatised teeth. Equally false positive results might delay treatment which might have an effect on the outcome, leading to the development of healing complications such as infection and root resorption. By collecting and analysing the clinical factors, we aim to identify which of aspects of the assessment might influence the prognoses of the teeth.

Conditions

Dental Trauma

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

Root canal treatment.

Once pulpal necrosis has been diagnosed, root canal treatment will be carried out by the patient's general practitioner. This is an end point for the tooth in the study.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• patients that have suffered dental trauma (lateral luxation)
• patients must have attended the Dental Trauma clinic within 2 weeks form the presenting injury
• patients should re-attend for review and monitor of teeth for at least 3 months following the injury
• patients older than 16 years old
• patients that have signed the informed consent

Exclusion Criteria

• patients presented more than 2 weeks following the injury
• patients suffered from injuries other than lateral luxation
• patients younger than 16 years old
• adults with incapacity
• patient that have not consented to take part

• Minimum Eligible Age: 16 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

NHS Lothian

OTHER_GOV

Sponsor Role: collaborator

University of Edinburgh

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Robert Philpott, BDS,

Role: PRINCIPAL_INVESTIGATOR

bob.philpott@ed.ac.uk

Locations

Edinburgh Dental Institute

Edinburgh, , United Kingdom

Countries

United Kingdom

Other Identifiers

AC18118

Identifier Type: -

Identifier Source: org_study_id