Physical Fitness, Body Composition and Frailty in Elderly People.Exercise Program Effecsts. EXERNET Elder 3.0

NCT ID: NCT03831841

Last Updated: 2020-07-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-11-05

Study Completion Date

2019-12-04

Brief Summary

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One of the major changes occurring in developed societies is a significant ageing of the population. Nowadays, because of an enhanced life expectancy, 17% of the Spanish population is composed of people over 65 and the number is expected to rise to 33% in 2050. Aging is characterized by a gradual lifelong accumulation of molecular and cellular damage that results in a progressive and generalized impairment in several bodily functions, an increased vulnerability to environmental challenges and a growing risk of disease and risk of death. These facts led to an increase on the prevalence of diseases such as osteoporosis diabetes, sarcopenia, obesity or frailty. However, lifestyles such as physical activity could attenuated aging process, maintaining the autonomy of elders, and it has been demonstrated that even implying guided exercise programs could reverse this condition of frailty and dependence.

In this way, the main aims of this research project are to analyze the effect of a multicomponent exercise program in frailty and pre-frailty people above 65 years and without cognitive impairment. Thus, it is going to be evaluated at the beginning and the end of the study; body composition, physical fitness, blood parameters including vitamin D and other health related parameters included in a questionnaire. Secondly, to study the perdurability of training-related gains over time.

Detailed Description

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The training will consist in a multicomponent exercise program, 3 days a week (Monday, Wednesday and Friday). It will take place during morning in groups of 10-14 and trainers will be qualified. Alll the exercise will be adapted for different levels of frailty and for their functional capacity.

Conditions

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Frail Elderly Syndrome Sarcopenia Physical Activity

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intervention

Multicomponent exercise programe involving all physical fitness paramenters and consisting on sesions of 1 hour, 3 days a week.

Group Type EXPERIMENTAL

Multicomponent exercise programe

Intervention Type BEHAVIORAL

An intervention consisting of training by a multicomponent program 3 times a week, working on aerobic capacity, flexibility, balance and strength.

Control

Control group with no intervention programe

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Multicomponent exercise programe

An intervention consisting of training by a multicomponent program 3 times a week, working on aerobic capacity, flexibility, balance and strength.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Above 65 years
* frailty of pre-frailty by SPPB.

Exclusion Criteria

* Severe cognitive impairment
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad de Zaragoza

OTHER

Sponsor Role lead

Responsible Party

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German Vicente-Rodríguez

Senior lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Universidad de Zaragoza

Zaragoza, , Spain

Site Status

Countries

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Spain

References

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Subias-Perie J, Navarrete-Villanueva D, Fernandez-Garcia AI, Moradell A, Alcala-Nalvaiz JT, Groessl EJ, Ara I, Vila-Maldonado S, Perez-Gomez J, Gonzalez-Gross M, Gomez-Cabello A, Vicente-Rodriguez G, Casajus JA. Cost-effectiveness of a multicomponent training programme for older adults with decreased functional capacity: An economic evaluation. Exp Gerontol. 2025 Sep 25;211:112911. doi: 10.1016/j.exger.2025.112911. Online ahead of print.

Reference Type DERIVED
PMID: 41015204 (View on PubMed)

Moradell A, Iguacel I, Navarrete-Villanueva D, Fernandez-Garcia AI, Gonzalez-Gross M, Perez-Gomez J, Ara I, Casajus JA, Gomez-Cabello A, Vicente-Rodriguez G. Effects of a multicomponent training and a detraining period on cognitive and functional performance of older adults at risk of frailty. Aging Clin Exp Res. 2025 Apr 7;37(1):117. doi: 10.1007/s40520-025-03011-w.

Reference Type DERIVED
PMID: 40192885 (View on PubMed)

Subias-Perie J, Navarrete-Villanueva D, Fernandez-Garcia AI, Moradell A, Lozano-Berges G, Gesteiro E, Perez-Gomez J, Ara I, Gomez-Cabello A, Vicente-Rodriguez G, Casajus JA. Effects of a multicomponent training followed by a detraining period on metabolic syndrome profile of older adults. Exp Gerontol. 2024 Feb;186:112363. doi: 10.1016/j.exger.2024.112363. Epub 2024 Jan 19.

Reference Type DERIVED
PMID: 38244708 (View on PubMed)

Fernandez-Garcia AI, Moradell A, Navarrete-Villanueva D, Subias-Perie J, Perez-Gomez J, Ara I, Gonzalez-Gross M, Casajus JA, Vicente-Rodriguez G, Gomez-Cabello A. Effects of Multicomponent Training Followed by a Detraining Period on Frailty Level and Functional Capacity of Older Adults with or at Risk of Frailty: Results of 10-Month Quasi-Experimental Study. Int J Environ Res Public Health. 2022 Sep 29;19(19):12417. doi: 10.3390/ijerph191912417.

Reference Type DERIVED
PMID: 36231712 (View on PubMed)

Fernandez-Garcia AI, Gomez-Cabello A, Gomez-Bruton A, Moradell A, Navarrete-Villanueva D, Perez-Gomez J, Gonzalez-Gross M, Ara I, Casajus JA, Vicente-Rodriguez G. Effects of multicomponent training and detraining on the fitness of older adults with or at risk of frailty: results of a 10-month quasi-experimental study. Eur J Sport Sci. 2023 Aug;23(8):1696-1709. doi: 10.1080/17461391.2022.2104657. Epub 2022 Aug 11.

Reference Type DERIVED
PMID: 35876120 (View on PubMed)

Moradell A, Fernandez-Garcia AI, Navarrete-Villanueva D, Perez-Gomez J, Gesteiro E, Ara Royo I, Casajus JA, Gomez-Cabello A, Vicente-Rodriguez G. Does nutritional status influence the effects of a multicomponent exercise programme on body composition and physical fitness in older adults with limited physical function? Eur J Sport Sci. 2023 Jul;23(7):1375-1384. doi: 10.1080/17461391.2022.2092426. Epub 2022 Jul 11.

Reference Type DERIVED
PMID: 35816744 (View on PubMed)

Other Identifiers

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EXERNET Elder 3.0

Identifier Type: -

Identifier Source: org_study_id

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