Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
90 participants
OBSERVATIONAL
2019-03-03
2020-10-14
Brief Summary
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This study will evaluate exosomal PD-1/PD-L1 expression in patients with OSAS as compared to controls and will further investigate their impact on immune cells function and proliferation capacities.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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OSAS patients
45 patients investigated for suspected OSAS with an apnea hypopnea index ≥15 per hour
PD1/PD-L1 exosomal expression
exosomal PD1/PD-L1 expression
Non OSAS patients
45 patients investigated for suspected OSAS with an apnea hypopnea index \<15 per hour
PD1/PD-L1 exosomal expression
exosomal PD1/PD-L1 expression
Interventions
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PD1/PD-L1 exosomal expression
exosomal PD1/PD-L1 expression
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Cancer past history
* Pregnant women
* Cognitif impairment
18 Years
ALL
No
Sponsors
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University Hospital, Angers
OTHER_GOV
Responsible Party
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Locations
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Laboratoire du Sommeil, Département de Pneumologie, CHU d'Angers
Angers, , France
Countries
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Other Identifiers
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2019-A00029-48
Identifier Type: -
Identifier Source: org_study_id
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