Adolescent Depression Associated With Parental Depression

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-28

Study Completion Date

2021-03-11

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care.

In children the existence of a parental depression is a significant and recognized risk factor for the development of a depression. It is regularly reported that 30% of adolescents of depressed parents have depression themselves. General Practitioners (GP) have significant access to the depression of adults, potentially parents of teenagers. In fact, 20% of patients in the regular active file of one GP have depression. The primary health care system could provide indirect but voluminous and unprecedented access to the identification of adolescent depression at an early stage from the encounter of depressed parents.

The difficulties of articulation between primary care (PC) and mental health devices are demonstrated. They disrupt the care pathways of adolescents detected in PC, prevention, and may even disturb early detection of depression. An organized joint between the PC and a specialized mental health service for adolescents ("Maison Des Adolescents" MDA) could promote the process of screening and preventing depression of adolescents of depressed parents encountered in PC.

In addition, if the effects of parental depression on adolescents are established, they remain complex and interactive. They vary by age and sex of the child but also the sex of the parent. A concomitant study of adolescent and parent depression will provide data to analyze the prevalence of depressed parent adolescent depression and to define risk or protection factors.

AdoDesP study is a cluster randomised trial (randomisation of the GPs) which compare a group of adolescent with PC articulated with mental health service (MDA) and an other group without articulation (routine cares).

A third group of depressed adolescents will be constituted to analyse parental depression of depressed adolescents.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Paternal Involvement in Psychiatric Care of Adolescents Managed for Depression or Suicide Attempt

NCT03661008

Psychiatric Disorder Depression Suicide, Attempted +1 more

UNKNOWN

PRimary Prevention Of Depression in Offspring of Depressed Parents

NCT02115880

Depression

COMPLETED NA

Efficacity of Psychological Intervention on Reducing the Suicidal Ideations, Depression Level and Improving Reinsertion

NCT03655730

Depressive Symptoms

COMPLETED NA

Reaching Out to Adolescents With Depression

NCT01140464

Depression

COMPLETED NA

Preventing Depression in the Children of Depressed African American Mothers

NCT00904917

Depression

COMPLETED PHASE1

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Depression

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PC articulated with MDA

Depressed parent encountered in PC for confirmation of depression with Hopkins Symptom Checklist-25 (HSCL25) scale. If confirmed, the adolescent will also be encountered by the GP for a screening test of depression (Adolescent Depression Rating Scale - ADRS). If negative, the patient will go out of the study. If positive, 2 others tests will be performed to study the intensity of the depression (Child depressionInventory - CDI) and the quality of life (Pediatric Quality of Life InventoryTM).Finally, the patient will be oriented to the MDA of Brest and will meet again the GP at 6 and 12 month to answers the same tests.

Group Type EXPERIMENTAL

MDA

Intervention Type OTHER

Depressed adolescents of depressed parents will be oriented to the MDA of Brest for depression cares.

Routine cares

Depressed parent encountered in PC for confirmation of depression with Hopkins Symptom Checklist-25 (HSCL25) scale. If confirmed, the adolescent will also be encountered by the GP for a screening test of depression (Adolescent Depression Rating Scale - ADRS). If negative, the patient will go out of the study. If positive, 2 others tests will be performed to study the intensity of the depression (Child depressionInventory - CDI) and the quality of life (Pediatric Quality of Life InventoryTM). Finally, the patient will be oriented to the routine cares and will meet again the GP at 6 and 12 month to answers the same tests.

Group Type ACTIVE_COMPARATOR

Routine Cares

Intervention Type OTHER

Depressed adolescents of depressed parents will be oriented to routine cares for depression cares.

Parental depression

Parental depression will be studied. Depressed adolescent encountered in MDA of Marseille for confirmation of depression with 3 tests : ADRS, CDI and PedsQL. If positive, the parent will come to the MDA for a screening test of depression (HSCL25). Parents and adolescent are seen only once.

Group Type EXPERIMENTAL

Parental depression

Intervention Type OTHER

Parents of depressed adolescents will be met for a screening test of depression.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MDA

Depressed adolescents of depressed parents will be oriented to the MDA of Brest for depression cares.

Intervention Type OTHER

Routine Cares

Depressed adolescents of depressed parents will be oriented to routine cares for depression cares.

Intervention Type OTHER

Parental depression

Parents of depressed adolescents will be met for a screening test of depression.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Parents of groups 1 and 2 :

* Major patient consulting his GP
* Depressed patient
* Parent of adolescent aged between 11 and 18 years old
* Adolescents of groups 1 and 2 :

* Aged more than 11 and less than 18 years old
* Parent included in the study
* Parents of group 3 :

* Parent of depressed adolescent under care at the MDA of Marseille, included in the study and whose depression is confirmed by HSCL25 scale
* Adolescents of group 3 :

* Aged more than 11 and less than 18 years old
* Depressed patient
* Under care at the MDA of Marseille since less than 1 month

Exclusion Criteria

* Parents of groups 1, 2 and 3 :

* Minor patient
* Enable to give his consent
* Patient with guardianship or curatorship
* Non consenting patient
* Pregnant or nursing mother
* Adolescents of groups 1 and 2 :

* Aged \< 11 or ≥18
* Parent whose depression isn't confirmed by HSCL25 scale
* Non consenting adolescent
* Pregnant or nursing mother
* Adolescent of group 3 :

* Aged \< 11 or ≥18
* Non depressed adolescent
* Non consenting patient
* Pregnant or nursing mother

Minimum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No