Cord Blood Nesfatin-1 and Irisin in the Intrauterine Growth Restricted Fetuses

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2019-01-15

Brief Summary

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: The aim of this study is to investigate Cord blood irisin and nesfatin-1 levels in pregnancies with intrauterine growth retardation and to determine whether they are associated with abnormal fetal doppler findings or not.

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Detailed Description

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This study was conducted at Yüzüncü Yıl University Medical Faculty Obstetrics and Gynecology Clinic. The study group included 34 pregnant women ranged from 18 to 45 years old who have intrauterine growth retardation and underwent ceseraen section. 32 pregnant women who had no abnormality on prenatal follow-up and underwent elective ceserean seciton served as control group. The maternal age, height, weight, body mass index (BMI), systolic and diastolic blood pressures were recorded in both groups of patients. Maternal serum total blood count and biochemical parameters were obtained from the laboratory parameters. Gestational week at birth, birth weight, sex, 1st and 5th minute APGAR scores were recorded. Blood samples were collected from all the cases during the cesarean section for measurmenet of nesfatin-1 and irisin by doubly clamped umbilical cord. Blood samples were immediately centrifuged in sterile tubes and maintained at -80 ° C until assessed.

Conditions

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Nesfatin-1 Irisin Intrauterine Growth Restriction

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Study group

Pregnancies complicated with intrauterine growth restricted fetuses

cord blood specimen during the delivery

Intervention Type OTHER

The cord blood will be taken during the delivery of baby.

Control group

Healthy pregnancies

cord blood specimen during the delivery

Intervention Type OTHER

The cord blood will be taken during the delivery of baby.

Interventions

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cord blood specimen during the delivery

The cord blood will be taken during the delivery of baby.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Pregnant women with intrauterine grwoth rectricted fetuses.
* Healthy pregnancies

Exclusion Criteria

* Pregnant women with chronic medical conditions
* multiple pregnancies
* fetuses with fetal malfomations or genetic syndromes
* pregnant women older than 45 years old

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No