Cerebral Desaturation and Postoperative Dysfunction After Thoracic Surgery

NCT ID: NCT03805880

Last Updated: 2019-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2018-07-31

Brief Summary

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The purpose of this study prospective observational study is to determine cognitive dysfunction incidence after thoracic surgery. We also evaluate evaluate the role of cerebral oxygen desaturations and hypertension as risk factors for post-operative cognitive dysfunction (POCD) in patients undergoing lung resection.

Detailed Description

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Conditions

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Thoracic Surgery Cognitive Dysfunction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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cerebral desaturation monitoring and cognitive examination

Before general anesthesia, continuous monitoring of cerebral oxygenation(rSO2) was started using an INVOS 5100 (Somaneic, Tro, MI) .Patient cognitive function was assessed using Mini-Mental State Examination (MMSE) on the day before surgery (baseline) and then after 1 day after surgery.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* patients scheduled for elective lobectomy or wedge resection via thoracotomy
* one lung ventilation (OLV duration) ≥ 45 min

Exclusion Criteria

* previous cerebral disease,
* dementia,
* severe cognitive dysfunction
* emergency surgery
* pregnancy
* patient refusal to give consent
* inability to give consent
* age ≤18 years
* ASA ≥ IV.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Roma La Sapienza

OTHER

Sponsor Role lead

Responsible Party

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Silvia Fiorelli

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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azienda ospedaliero universitaria Sant'Andrea

Roma, , Italy

Site Status

Countries

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Italy

Other Identifiers

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SATURIMETRIA

Identifier Type: -

Identifier Source: org_study_id

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