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Early Debridement Within 24 Hours After Surgery for Wound Healing of Abdominal Incision

NCT ID: NCT03798041

Last Updated: 2021-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

480 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-01

Study Completion Date

2021-03-16

Brief Summary

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Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.

Detailed Description

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Conditions

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Surgical Wound

Keywords

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Surgical Wound Suture, Complication

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Debridement group

The subjects in this group will be debrided within 24 hours after surgery.

Group Type EXPERIMENTAL

Debridement Within 24 Hours After Surgery

Intervention Type BEHAVIORAL

Debrided within 24 hours after surgery

Control group

The subjects in this group will experience wound dressing change regularly 24 hours after surgery.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Debridement Within 24 Hours After Surgery

Debrided within 24 hours after surgery

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* the patient with major abdominal incision.

Exclusion Criteria

* Pregnant woman
* Patient with diabetes
* Patient with a history of cardiovascular disease, including coronary heart disease and stroke.
* Severe lung diseases such as COPD and asthma
* Patients undergoing emergent surgery or infectious surgery
* Patients with surgical site infection or abdominal abscess
* No autonomy, inability or unwillingness to participate in follow-up
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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First Affiliated Hospital Xi'an Jiaotong University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xu-Feng Zhang, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

First Affiliated Hospital Xi'an Jiaotong University

Locations

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The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, China

Site Status

Countries

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China

Other Identifiers

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XJTU1AFCRC2017SJ-007-1

Identifier Type: -

Identifier Source: org_study_id