Continuous Subcutaneous Insulin Infusion Versus Multiple Dose Insulin Injections in Routine Clinical Practice

NCT ID: NCT03793283

Last Updated: 2020-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2019-12-31

Brief Summary

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Observational study about effectiveness and safety of continuous subcutaneous insulin infusion compared to multiple dose insulin injections in Type 1 Diabetes Mellitus (T1DM) adult patients in routine clinical practice.

Detailed Description

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Cross-sectional analysis about effectiveness and safety of continuous subcutaneous insulin infusion compared to multiple dose insulin injections in T1DM adult patients in routine clinical practice.

All clinical variables are gathered from four EMR softwares (Mambrino XXI, Carelink Pro®, Emminens eConecta® and FreeStyle Libre®).

Data analysis is conducted using SPSS (Chicago, IL) statistics software. Results are presented as mean ± SD values or percentages. A paired Student's t-test or a Wilcoxon signed-rank test were used for the analysis of differences. Comparisons between proportions were analyzed using a chi-squared test. A P value \< 0.05 was considered statistically significant.

The protocol was approved by the reference Castilla-La Mancha Public Health Institute Ethic Committee. All participants provided written informed consent.

Conditions

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Type 1 Diabetes Mellitus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Continous Subcutaneous Insulin Infusion

All T1DM adult patients attended in Ciudad Real General University Hospital and treated with CSII.

Forty-five patients are actually treated with CSII in our hospital.

CSII

Intervention Type DEVICE

Currently receiving CSII therapy during 6 or more months.

Multiple dose insulin injections (MDI):

Forty-five T1DM adult patients attended in Ciudad Real General University Hospital and treated with MDI.

MDI patients will be selected through simple random sampling (1:1) from our T1DM patient database.

Multiple dose insulin injections

Intervention Type DRUG

Currently receiving MDI therapy during 6 or more months.

Interventions

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CSII

Currently receiving CSII therapy during 6 or more months.

Intervention Type DEVICE

Multiple dose insulin injections

Currently receiving MDI therapy during 6 or more months.

Intervention Type DRUG

Other Intervention Names

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Continuous subcutaneous insulin infusion MDI

Eligibility Criteria

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Inclusion Criteria

* ≥18 years of age.
* Diagnosed of Type 1 Diabetes Mellitus.
* Be attended in Ciudad Real General University Hospital.
* Current treated with CSII (CSII cohort) or MDI (MDI cohort) during ≥6 months.

Exclusion Criteria

* Less than 18 years old.
* Other types of diabetes mellitus.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Castilla-La Mancha

OTHER

Sponsor Role collaborator

Universidad de Córdoba

OTHER

Sponsor Role collaborator

Castilla-La Mancha Health Service

OTHER

Sponsor Role lead

Responsible Party

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Jesús Moreno Fernández

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jesus Moreno-Fernandez, PhD

Role: PRINCIPAL_INVESTIGATOR

Castilla-La Mancha Public Health Service.

Locations

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Obispo Rafael Torija, St.

Ciudad Real, , Spain

Site Status

Countries

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Spain

Other Identifiers

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C-225

Identifier Type: -

Identifier Source: org_study_id

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