A Study of Technology to Improve Glucose Control in Participants With Type 1 Diabetes

NCT ID: NCT03758430

Last Updated: 2020-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

28 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-02-06

Study Completion Date

2020-08-07

Brief Summary

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The main purpose of this study is to determine whether combining meal, glucose, and insulin data in a web-based system will improve management of type 1 diabetes (T1D). No study drug will be given. The study will last about 18 weeks.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 1

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Combined Diabetes Management Data

Participants with type 1 diabetes will use a meal tagging application (app) and fitness tracker. They will upload these data to a web portal where they will be matched with data from their continuous glucose monitor and insulin pump. Combined data will be used for diabetes management.

Meal-Tagging App

Intervention Type OTHER

Meal tagging app to capture frequently eaten meals and test meals for 16 weeks.

Fitness Tracker

Intervention Type DEVICE

Fitness tracker will be worn around the clock for 16 weeks.

Interventions

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Meal-Tagging App

Meal tagging app to capture frequently eaten meals and test meals for 16 weeks.

Intervention Type OTHER

Fitness Tracker

Fitness tracker will be worn around the clock for 16 weeks.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* T1D by clinical diagnosis for \> 3 years
* Insulin pump use \> 3 months: must use one of the following pump types: Animas Ping and Vibe, Insulet Omnipod, Medtronic 523/723 and 530G, Tandem t:slim and t:flex
* Continuous Glucose Monitor (CGM) \> 3 months and current use of Dexcom G5 at least 6 out of 7 days per week
* HbA1c 7.0-9.5%
* Must have iPhone (meal-tagging app has been built on iOS)
* Personal computer for uploading of pump and CGM devices
* Willingness to follow study protocol including tagging food data
* Comfort speaking, reading, and writing English

Exclusion Criteria

* Individuals currently using a hybrid closed-loop system (e.g., Medtronic 670G)
* Individuals planning to follow a specific diet plan for weight loss
* Inability to consume "common meals"
* Gastroparesis;
* Eating disorder
* Evidence of missed insulin meal-time insulin boluses on pump download
* Use of medications that can affect blood glucose levels (such as SGLT inhibitors, steroid, beta agonists)
* Use of medications that affect gastric emptying (such as GLP agonists, pramlinitide)
* Alcohol abuse
* Pre-conception, pregnancy, or lactation
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Joslin Diabetes Center

OTHER

Sponsor Role collaborator

Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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Joslin Diabetes Center

Boston, Massachusetts, United States

Site Status

Countries

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United States

Other Identifiers

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F3Z-MC-IORA

Identifier Type: OTHER

Identifier Source: secondary_id

17111

Identifier Type: -

Identifier Source: org_study_id

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