Effects of Beverages Containing Orange or Apple Pomace on Digestive Health in Adults

NCT ID: NCT03749031

Last Updated: 2019-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-15

Study Completion Date

2019-08-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a randomized crossover intervention designed to evaluate effects of daily intake of beverages containing orange or apple Pomace on gastrointestinal function as measured by stool frequency. Additional outcomes will include aspects of digestive health and self-reported GI symptoms and dietary intake as well as analysis of gut microbiota.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Digestive Health

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Orange juice only

16 oz. orange juice per day for 4 weeks

Group Type PLACEBO_COMPARATOR

Orange Juice

Intervention Type OTHER

16 oz. orange juice per day for 4 weeks

orange juice + orange Pomace

16 oz. orange juice + orange Pomace per day for 4 weeks

Group Type EXPERIMENTAL

Orange juice + Orange Pomace

Intervention Type OTHER

16 oz. orange juice + orange Pomace per day for 4 weeks

Apple juice only

16 oz. apple juice per day for 4 weeks

Group Type PLACEBO_COMPARATOR

Apple Juice

Intervention Type OTHER

16 oz. apple juice per day for 4 weeks

Apple Juice + Apple Pomace

16 oz. apple juice + apple Pomace per day for 4 weeks

Group Type EXPERIMENTAL

Apple Juice and Apple Pomace

Intervention Type OTHER

16 oz. apple juice and apple Pomace per day for 4 weeks

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Orange juice + Orange Pomace

16 oz. orange juice + orange Pomace per day for 4 weeks

Intervention Type OTHER

Orange Juice

16 oz. orange juice per day for 4 weeks

Intervention Type OTHER

Apple Juice and Apple Pomace

16 oz. apple juice and apple Pomace per day for 4 weeks

Intervention Type OTHER

Apple Juice

16 oz. apple juice per day for 4 weeks

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Healthy males and females 18-60 years old
* Willing and able to consume 16 oz. of orange or apple beverage per day for 4 week periods
* Willing to maintain usual diet, smoking status, physical activity pattern, supplements and meds

Exclusion Criteria

* Food allergies or sensitivities to ingredients in study beverages
* Presence or history of GI condition, endocrine (including diabetes), cardiovascular disease or other disease or condition that could interfere in the interpretation of the study results in the opinion of the Investigator.
* Extreme dietary habits including vegetarian, vegan or Atkins diet
* Females or are pregnant, planning to become pregnant or breast feeding during the study period.
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

PepsiCo Global R&D

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Kathleen Kelley, MD

Role: PRINCIPAL_INVESTIGATOR

BioFortis

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

BioFortis

Addison, Illinois, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PEP-1805

Identifier Type: -

Identifier Source: org_study_id