Development of a Practical, Minimally Invasive Seizure Gauge

NCT ID: NCT03745118

Last Updated: 2023-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

95 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-11-19

Study Completion Date

2022-08-05

Brief Summary

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The researchers are trying to assess changes in physiological signals before and during seizures.

Detailed Description

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Subjects that are undergoing video EEG monitoring in the hospital for their epilepsy at Mayo Clinic will be consented to participate in this study for a minimum of two days and/or the duration of their hospital stay for their clinical care. Subjects will be asked to wear up to 4 different commercially available seizure detection devices and complete surveys.

In the second year of the study patients who have implanted devices capable of recording or detecting seizures will be recruited to wear a noninvasive biosensor for multiple months. This data will be used to develop algorithms capable of detecting and/or forecasting seizures.

When the subjects clinical EEG monitoring is completed data scientists will analyze the data to identify patterns.

Conditions

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Epilepsy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Monitoring Device

Subjects will be asked to wear up to 4 different noninvasive seizure detection devices including EpiTel EpiLog, Byte Flies Sensor Dots, Empatica E4, Biovotion Everion, GeneActiv

Group Type OTHER

EpiTel EpiLog

Intervention Type DEVICE

Plastic pad that is about the size of a house key, and will be adhered to your scalp with gel

Byte Flies Sensor Dots

Intervention Type DEVICE

Plastic pads that will be adhered to your chest area

Empatica E4

Intervention Type DEVICE

wearable seizure detection wristband

Biovotion Everion

Intervention Type DEVICE

wearable seizure detection device armband that is attached to upper arm

GeneActiv

Intervention Type DEVICE

wearable seizure detection watch

Interventions

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EpiTel EpiLog

Plastic pad that is about the size of a house key, and will be adhered to your scalp with gel

Intervention Type DEVICE

Byte Flies Sensor Dots

Plastic pads that will be adhered to your chest area

Intervention Type DEVICE

Empatica E4

wearable seizure detection wristband

Intervention Type DEVICE

Biovotion Everion

wearable seizure detection device armband that is attached to upper arm

Intervention Type DEVICE

GeneActiv

wearable seizure detection watch

Intervention Type DEVICE

Other Intervention Names

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Epilog Byteflies Sensor Dots E4 Wristband

Eligibility Criteria

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Inclusion Criteria

* Patients with epilepsy- scalp EEG or invasive EEG monitoring for clinical care, or an implanted device capable of monitoring brain activity and identifying seizures (e.g. NeuroPace RNS, Medtronic PC+S, Medtronic RC+S)
* Pediatric subjects 7 years of age or older.

Exclusion Criteria

* Cognitive or psychiatric condition rendering patient unable to cooperate with data collection, or manage and recharge smart watch and tablet computer devices.
* Presence of open or healing wounds near monitoring sites (infection risk).
Minimum Eligible Age

7 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Benjamin H. Brinkmann

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Benjamin (Ben) H. Brinkmann, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic

Rochester, Minnesota, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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18-008357

Identifier Type: -

Identifier Source: org_study_id

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