Blood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.

NCT ID: NCT03741166

Last Updated: 2021-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

871 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-11-08

Study Completion Date

2019-04-05

Brief Summary

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The primary objective of this sub-study, 2018-10B, is to collect blood specimens to assess new biomarkers for the detection of Colorectal Cancer (CRC).

Detailed Description

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Subjects who consent to enroll in Exact Sciences Protocol 2018-10, will be asked to participate in this sub-study. Subjects enrolled in the Exact Sciences Protocol 2018-10, who provide written informed consent to participate in this sub-study, will have a blood sample collected at enrollment.

Conditions

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Colo-rectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subject aged 45-49 with Average CRC Risk

Subjects will be men and women, 45-49 years of age, who enroll in Exact Sciences Protocol 2018-10. Subjects will provide a blood sample at time of enrollment.

Blood Sample Collection

Intervention Type OTHER

Subjects participating in the study will have blood drawn at enrollment.

Interventions

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Blood Sample Collection

Subjects participating in the study will have blood drawn at enrollment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Subject is currently enrolled in Exact Sciences Protocol 2018-10
2. Subject is willing and able to provide a blood sample.
3. Subject is willing and able to sign informed consent.

Exclusion Criteria

1\. Subject has any condition that in the opinion of the Investigator should preclude participation in the study.
Minimum Eligible Age

45 Years

Maximum Eligible Age

49 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Exact Sciences Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Thomas Imperiale

Role: PRINCIPAL_INVESTIGATOR

Indiana University

Locations

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Mayo Clinic Arizona

Phoenix, Arizona, United States

Site Status

Ventura County Gastroenterology

Camarillo, California, United States

Site Status

Alliance Research Centers

Laguna Hills, California, United States

Site Status

Focilmed

Oxnard, California, United States

Site Status

Desert Oasis Healthcare Medical Group

Palm Springs, California, United States

Site Status

Gastroenterology Associates of Fairfield County

Bridgeport, Connecticut, United States

Site Status

Yale University Section of Digestive Diseases and Liver Diseases

New Haven, Connecticut, United States

Site Status

Precision Clinical Research, LLC

Lauderdale Lakes, Florida, United States

Site Status

Northshore University Health System Evanston Hospital

Evanston, Illinois, United States

Site Status

DM Clinical Research- Southwest Gastroenterology

Oak Lawn, Illinois, United States

Site Status

Deaconess Clinic- Mt. Pleasant

Evansville, Indiana, United States

Site Status

Deaconess Clinic- Gateway

Newburgh, Indiana, United States

Site Status

Johnson County ClinTrials, LLC

Lenexa, Kansas, United States

Site Status

New Orleans Research Institue

Metairie, Louisiana, United States

Site Status

Delta Research Partners, LLC

Monroe, Louisiana, United States

Site Status

Louisiana Research Center

Shreveport, Louisiana, United States

Site Status

Investigative Clinical Research

Annapolis, Maryland, United States

Site Status

Centennial Medical Group

Elkridge, Maryland, United States

Site Status

Capitol Research

Rockville, Maryland, United States

Site Status

Commonwealth Clinical Studies

Brockton, Massachusetts, United States

Site Status

Mayo Clinic Rochester

Rochester, Minnesota, United States

Site Status

United Medical Associates

Binghamton, New York, United States

Site Status

Asheville Gastroenterology Associates

Asheville, North Carolina, United States

Site Status

Charlotte Gastroenterology & Hepatology, PLLC

Charlotte, North Carolina, United States

Site Status

Wilmington Gastroenterology Associates

Wilmington, North Carolina, United States

Site Status

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States

Site Status

Great Lakes Gastroenterology Research, LLC

Mentor, Ohio, United States

Site Status

Comprehensive Internal Medicine, Inc.

Wooster, Ohio, United States

Site Status

Family Practice Center of Wooster, Inc./Clinical Trial Developers

Wooster, Ohio, United States

Site Status

Gastroenterology Associates, PA

Greenville, South Carolina, United States

Site Status

Gastro One

Germantown, Tennessee, United States

Site Status

Quality Medical Research, PLLC

Nashville, Tennessee, United States

Site Status

Austin Regional Clinic

Austin, Texas, United States

Site Status

University of Texas Health Science Center- McGovern Medical School

Houston, Texas, United States

Site Status

DM Clinical Research- PCP for Life

Houston, Texas, United States

Site Status

Virginia Gastroenterology Institute

Suffolk, Virginia, United States

Site Status

Wisconsin Center for Advanced Research

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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2018-10B

Identifier Type: -

Identifier Source: org_study_id

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