Association Between Different Blood Groups and Sepsis in Preterm Infants

NCT ID: NCT03734978

Last Updated: 2018-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-12-15

Study Completion Date

2019-10-31

Brief Summary

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To investigate whether there is a relationship between sepsis and blood groups in preterm infants.This retrospective cohort study included preterm neonates born at \<32 weeks of gestation with a birth weight \<1500 g. Neonates were grouped by blood type (O, A, B, AB) and sepsis were compared among these groups.

Detailed Description

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This retrospective study was conducted on data collected between 1 January 2011 and 31 August 2018 in the neonatal intensive care unit (NICU) of the Health Sciences University Zekai Tahir Burak Women's Health Education and Research Hospital.

Neonates born at GA \<32 weeks with birth weight (BW) \<1500 g were included in the study.

Data pertaining to the neonates were recorded from medical records for each patient, and their ABO blood type was recorded.

The neonates were grouped by blood type (O, A, B, AB) and also separated into non-O (A, B, AB) and O groups and non-A (O, B, AB) and A groups for comparison of early and late onset sepsis.

Conditions

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Blood Group Antigen Abnormality Prematurity Sepsis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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A blood group

prematurity with sepsis

Diagnosis

Intervention Type DIAGNOSTIC_TEST

biochemistry

O blood group

prematurity with sepsis

Diagnosis

Intervention Type DIAGNOSTIC_TEST

biochemistry

B blood group

prematurity with sepsis

Diagnosis

Intervention Type DIAGNOSTIC_TEST

biochemistry

AB blood group

prematurity with sepsis

Diagnosis

Intervention Type DIAGNOSTIC_TEST

biochemistry

Interventions

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Diagnosis

biochemistry

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Preterm neonates born at \<32 weeks of gestation with a birth weight \<1500 g.

Exclusion Criteria

* Neonates born with severe congenital defects, birth weight ≥1500 g and gestational age ≥32 weeks were excluded.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zekai Tahir Burak Women's Health Research and Education Hospital

OTHER

Sponsor Role collaborator

Ufuk Cakir

OTHER

Sponsor Role lead

Responsible Party

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Ufuk Cakir

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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ufuk cakir

Role: PRINCIPAL_INVESTIGATOR

Zekai Tahir Burak Women's Health Research and Education Hospital

Locations

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Zekai Tahir Burak Hospital

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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ufuk cakir

Role: CONTACT

05058581781

Facility Contacts

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ufuk cakir, M.D.

Role: primary

5058581781

cuneyt tayman, prof

Role: backup

Other Identifiers

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BGaPS

Identifier Type: -

Identifier Source: org_study_id

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