Sarcopenia and Orthostatic Hypotension

NCT ID: NCT03732716

Last Updated: 2018-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-09-10

Study Completion Date

2018-12-31

Brief Summary

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Elderly patients generally have a tendency for having sarcopenia which refers to muscle loss that may be related to many factors. These patients also have a tendency to falls and injuries. Whether elderly sarcopenic patients have abrupt blood pressure drops upon standing remains unknown. Therefore, in this study, we sought to determine the incidence of orthostatic hypotension in sarcopenic elderly patients and compare it with elderly patients with no sarcopenia.

Detailed Description

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Conditions

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Orthostatic Hypotension Sarcopenia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Elderly with sarcopenia

50 patients aged 75 or older with sarcopenia Intervention: Each patient's supine and standing blood pressures will be measured.

blood pressure measurement

Intervention Type DIAGNOSTIC_TEST

Intervention: Each patient's supine and standing blood pressure measurements will be recorded

Elderly without sarcopenia

50 patients aged 75 or older without sarcopenia Intervention: Each patient's supine and standing blood pressures will be measured.

blood pressure measurement

Intervention Type DIAGNOSTIC_TEST

Intervention: Each patient's supine and standing blood pressure measurements will be recorded

Interventions

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blood pressure measurement

Intervention: Each patient's supine and standing blood pressure measurements will be recorded

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients 75 years or older

Exclusion Criteria

* Pace-maker
* End stage renal insufficiency
* End stage malignancy
* Dehydration
* Severe anemia ( Hgb \< 8 gr/dl)
* Acute infection
* Marked edema
* Neurodegenerative disease
Minimum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sisli Hamidiye Etfal Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Kudret Keskin

Principle Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kadriye Orta Kılıçkesmez, Prof

Role: STUDY_DIRECTOR

Şişli Hamidiye Etfal Education and Research Hospital

Locations

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Şişli Hamidiye Etfal Education and Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Kudret Keskin, MD

Role: CONTACT

0212 3735000 ext. 5188

Facility Contacts

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Kudret Keskin, MD

Role: primary

212 3735000 ext. 5188

References

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Hashimoto Y, Kaji A, Sakai R, Hamaguchi M, Okada H, Ushigome E, Asano M, Yamazaki M, Fukui M. Sarcopenia is associated with blood pressure variability in older patients with type 2 diabetes: A cross-sectional study of the KAMOGAWA-DM cohort study. Geriatr Gerontol Int. 2018 Sep;18(9):1345-1349. doi: 10.1111/ggi.13487. Epub 2018 Jul 24.

Reference Type BACKGROUND
PMID: 30039599 (View on PubMed)

Other Identifiers

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2052

Identifier Type: -

Identifier Source: org_study_id

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