Sarcopenia in Axial and Peripheral Spondyloarthropathies
NCT ID: NCT03319264
Last Updated: 2025-12-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
106 participants
INTERVENTIONAL
2017-11-02
2018-07-04
Brief Summary
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The aim is to conduct the first French study on the prevalence and severity of sarcopenia in patients with spondyloarthropathies and to study the variables that may be associated with it. Finally, we propose to evaluate obesity related to sarcopenia in these patients and compare them to cases matched for age and sex (from OFELY / STRAMBO cohorts, Lyon, FRANCE).
This is a prospective interventional and monocentric study with minimal risks and constraints: patients will be included for one day for an evaluation of their sarcopenia by measuring their muscle strength, physical performance and body composition and recording of their socio-demographic and disease characteristics.
Detailed Description
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Conditions
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Keywords
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Study Design
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NA
SINGLE_GROUP
SCREENING
NONE
Study Groups
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Patients with SpA
Patients included in this single group study will have 3 interventions to assess the severity of muscle loss :
* dynamometry exam
* walking test
* Dual-energy X-ray Absorptiometry (DXA) measurement Quality of life will be assessed with Sarcopenia \& Quality of Life (SARQOL) questionnaire. Patients will also fill a Life habits Questionnaire.
Dynamometry exam
Prehension strength of the main hand will be assessed thanks to dynamometry, in order to evaluate patient's muscular strength
Walking test
A 4 metres walking test will be performed to assess patient's walking speed
DXA measurement
DXA measurement will be performed to assess patient's body composition
SARQOL questionnaire
Patient's quality of life will be assessed thanks to the SARQOL questionnaire
Life habits Questionnaire
Life habits Questionnaire
Interventions
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Dynamometry exam
Prehension strength of the main hand will be assessed thanks to dynamometry, in order to evaluate patient's muscular strength
Walking test
A 4 metres walking test will be performed to assess patient's walking speed
DXA measurement
DXA measurement will be performed to assess patient's body composition
SARQOL questionnaire
Patient's quality of life will be assessed thanks to the SARQOL questionnaire
Life habits Questionnaire
Life habits Questionnaire
Eligibility Criteria
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Inclusion Criteria
* Hospitalized or attending the rheumatology department for spondyloarthopathy.
Exclusion Criteria
* Immobilization for a period of more than 15 days during the last 3 months
* pregnant or breastfeeding woman
* Not affiliated to the national healthcare insurance
* difficulty in understanding French
* psychiatric disorder
18 Years
80 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Locations
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Service de Rhumatologie - Hôpital Edouard Herriot
Lyon, , France
Countries
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References
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Merle B, Cottard M, Sornay-Rendu E, Szulc P, Chapurlat R. Spondyloarthritis and Sarcopenia: Prevalence of Probable Sarcopenia and its Impact on Disease Burden: The Saspar Study. Calcif Tissue Int. 2023 Jun;112(6):647-655. doi: 10.1007/s00223-023-01074-3. Epub 2023 Mar 21.
Other Identifiers
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2017-A02391-52
Identifier Type: OTHER
Identifier Source: secondary_id
69HCL17_0145
Identifier Type: -
Identifier Source: org_study_id