Diagnostic Value and Biological Significant of cd71 in Lymphoid Disorders
NCT ID: NCT03720977
Last Updated: 2018-10-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
139 participants
OBSERVATIONAL
2019-12-01
2020-12-01
Brief Summary
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Detailed Description
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* CBC.
* Bone marrow aspiration morphology.
* Cytochemistry.
* Flow cytometry immunophenotyping.
* Bone marrow biopsy when indicated.
2. Special investigation is flow cytometry examination of CD71 expression.
sample size calculation ; sample size cases 39 sample size controls 39 total sample size 79 sample will be collected from patient in hospital university ,Data will be analysed by SPSS program
Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Marwa Aboelim Shafeik
OTHER
Responsible Party
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Marwa Aboelim Shafeik
Principal investigator
Principal Investigators
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Maged Salah, Prof
Role: STUDY_DIRECTOR
Assiut University .clinical pathologydepartment
Central Contacts
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Tagreed kamal, dr
Role: CONTACT
References
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Zhang Q, Steensma DP, Yang J, Dong T, Wu MX. Uncoupling of CD71 shedding with mitochondrial clearance in reticulocytes in a subset of myelodysplastic syndromes. Leukemia. 2019 Jan;33(1):217-229. doi: 10.1038/s41375-018-0204-z. Epub 2018 Jul 26.
Salzberger W, Martrus G, Bachmann K, Goebels H, Hess L, Koch M, Langeneckert A, Lunemann S, Oldhafer KJ, Pfeifer C, Poch T, Richert L, Schramm C, Wahib R, Bunders MJ, Altfeld M. Tissue-resident NK cells differ in their expression profile of the nutrient transporters Glut1, CD98 and CD71. PLoS One. 2018 Jul 20;13(7):e0201170. doi: 10.1371/journal.pone.0201170. eCollection 2018.
Dunsmore G, Koleva P, Ghobakhloo N, Sutton R, Ambrosio L, Meng X, Hotte N, Nguyen V, Madsen KL, Dieleman LA, Huang V, Elahi S. Lower Abundance and Impaired Function of CD71+ Erythroid Cells in Inflammatory Bowel Disease Patients During Pregnancy. J Crohns Colitis. 2019 Feb 1;13(2):230-244. doi: 10.1093/ecco-jcc/jjy147.
Other Identifiers
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diagnostic value of cd71
Identifier Type: -
Identifier Source: org_study_id
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