Clinico-radiological Correlation of MRI Findings in Patients With Temporomandibular Joint Disc Perforation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

282 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-11-01

Study Completion Date

2025-12-03

Brief Summary

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To evaluate the presence of TMJ disc perforation on MRI and investigate its associations with internal disc derangements, disc configuration, condylar bone marrow signal patterns, joint effusion, and demographic or clinical variables such as age, sex, dental status, and pain severity.

Detailed Description

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This study will prospectively evaluate temporomandibular joint (TMJ) disc perforation using magnetic resonance imaging (MRI) in a diverse adult population. The investigation will focus on identifying the prevalence of disc perforation and examining its relationship with key TMJ structural and functional parameters. Specifically, the study will assess internal disc derangements, variations in disc morphology, condylar bone marrow signal characteristics, and the presence of joint effusion. In addition, demographic and clinical factors-including age, sex, dental status, and pain severity-will be analyzed to determine their potential association with disc perforation.

MRI-based assessments will be performed using standardized imaging protocols, and all findings will be systematically recorded and evaluated. By integrating radiologic and clinical data, the study aims to improve the understanding of factors contributing to TMJ disc perforation and to support future diagnostic and therapeutic strategies.

Conditions

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Temporomandibular Joint Disc Displacement Magnetic Resonance Imaging Bone Marrow

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group 1: Disc Perforation Group

Participants who demonstrate temporomandibular joint (TMJ) disc perforation on MRI. This cohort will be used to evaluate imaging characteristics and clinical parameters associated with perforation.

No interventions assigned to this group

Group 2: Non-Perforation Group

Participants without MRI evidence of TMJ disc perforation.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with available temporomandibular joint (TMJ) MRI scans (both open- and closed-mouth)
* Age ≥14 years
* Complete clinical records including Visual Analogue Scale (VAS) pain scores and dental status
* Willingness to participate in the study and provide informed consent (for prospective studies)

Exclusion Criteria

* Presence of systemic disorders affecting bone metabolism, including rheumatoid arthritis, chronic systemic corticosteroid therapy, Paget's disease, hypo- or hyperparathyroidism, osteomalacia, or renal osteodystrophy
* History of medications that could alter bone architecture
* Current orthodontic treatment
* History of head and neck trauma or surgery
* Presence of head and neck cystic or tumoral pathology
* Prior radiotherapy or chemotherapy
* Pregnancy
* Presence of ferromagnetic objects in the head (contraindication to MRI)

Minimum Eligible Age

14 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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DİLARA NİL GÜNAÇAR

Assoc. Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Recep Tayyip Erdoğan University Faculty of Dentistry

Rize, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2025/48

Identifier Type: -

Identifier Source: org_study_id