Registry Evaluating AF Ablation Techniques

NCT ID: NCT03695484

Last Updated: 2022-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

212 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-31

Study Completion Date

2022-06-30

Brief Summary

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The purpose of this observational registry is to prospectively collect procedure efficiency, safety and acute and long term outcome data from catheter ablation procedures as treatment of paroxysmal atrial fibrillation, using the following treatment modalities:

* Cryoballoon ablation
* Manual guided RF ablation using Contact Force catheters
* Remote Magnetic Navigation guided RF ablation with e-Contact and high power settings
* Remote Magnetic Navigation guided RF ablation with e-Contact and low power settings

Detailed Description

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Conditions

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Atrial Fibrillation Catheter Ablation

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Manual guided RF ablation

Patients with paroxysmal atrial fibrillation treated with Manual guided RF ablation using Contact Force catheters

No interventions assigned to this group

Cryoballoon ablation

Patients with paroxysmal atrial fibrillation treated with Cryoballoon ablation. Cryoballoon: Arctic Front Advance, Medtronic - 28 mm

No interventions assigned to this group

RMN guided RF ablation - High power

Patients with paroxysmal atrial fibrillation treated with Remote Magnetic Navigation guided RF ablation with e-Contact and high power settings.

High power ablation settings: a minimum of 40 Watt, 43grC, flow 17ml/min. Higher voltages (e.g. anterior wall) are allowed with respect to the operators' preference.

No interventions assigned to this group

RMN guided RF ablation - Low power

Patients with paroxysmal atrial fibrillation treated with Remote Magnetic Navigation guided RF ablation with e-Contact and low power settings.

Low power ablation settings: a maximum of 39 Watt, 43grC, flow 17ml/min. Lower voltages are allowed with respect to the operators' preference.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Documented Paroxysmal Atrial Fibrillation
* Eligibility for Pulmonary Vein Isolation by catheter ablation based on the respective ACC/AHA/ESC Guideline valid at the date of procedure
* Signed the informed consent to participate in the registry

Exclusion Criteria

* Younger than 18 years of age
* Prior AF ablation procedure (including MAZE procedure)
* Prior ablation of Non-AF Arrhythmia within 3 months of enrollment
* Presence of cardiac thrombus
* Other AF ablations performed during procedure (e.g. lines, rotor, CFAE's etc)
* Active endocarditis or systemic infection
* Life expectancy \< 1 year
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Erasmus Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Anne-Marie Noten

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ziekenhuis Netwerk Antwerpen

Antwerp, , Belgium

Site Status

Erasmus MC

Rotterdam, , Netherlands

Site Status

E. Meshalkin National medical research center

Novosibirsk, , Russia

Site Status

Countries

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Belgium Netherlands Russia

Other Identifiers

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PRIME-AF

Identifier Type: -

Identifier Source: org_study_id

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