IPACK Block in Total Knee Arthroplasty

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE2

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2020-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed preoperatively and group B (n=50) where an adductor canal block only will be performed preoperatively. All patients will receive a standardized multimodal approach, including pregabalin, paracetamol, and PCA with morphine. NRS scores in static and dynamic conditions during the first 48 hours postoperatively, morphine consumption during the first 24 hours postoperatively will be measured and additionally, patient satisfaction, complications, range of knee motion, moblization, functionality, delirium ocurence will be recorded. Chronic pain will be assessed in 3 and 6 months postoperatively.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Analgesic Efficacy of Protocol for Primary Total Knee Arthroplasty (TKA)

NCT03703206

Knee Arthroplasty, Total

COMPLETED PHASE3

Comparision of IPACK and Periarticular Block With Adductor Block Alone After Total Knee Artroplasty

NCT04931966

Osteo Arthritis Knee

COMPLETED NA

Adductor Canal Block and IPACK Block vs Adductor Canal Block and the Gastrosoleus Interfascial Block After Total Knee Arthroplasty

NCT07336901

Pain After Knee Arthroplasty

NOT_YET_RECRUITING NA

IPACK Nerve Block for Total Knee Arthroplasty

NCT03921034

Arthropathy of Knee Anesthesia

COMPLETED PHASE4

Comparison of IPACK Block and PCI for Postoperative Analgesia and Function Recovery Following Total Knee Arthroplasty

NCT05943080

Total Knee ArthroplastyKnee Pain, Functionality

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Total Knee Arthroplasty

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group A

Group Type ACTIVE_COMPARATOR

Adductor Canal Block plus IPACK Block

Intervention Type DRUG

Adductor Canal Block plus IPACK Block using Ropivacaine

Group B

Group Type ACTIVE_COMPARATOR

Adductor Canal Block

Intervention Type DRUG

Adductor Canal Block using Ropivacaine

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Adductor Canal Block plus IPACK Block

Adductor Canal Block plus IPACK Block using Ropivacaine

Intervention Type DRUG

Adductor Canal Block

Adductor Canal Block using Ropivacaine

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Physical status according to American Society of Anesthesiologists (ASA) I-III
* Patients scheduled for total knee arthroplasty

Exclusion Criteria

* Previous operation on same knee
* Contraindication of spinal anesthesia, peripheral nerve blocks or any of the agents used in the protocol
* BMI above 32
* Serious psychiatric, mental and cognitive disorders
* Language barrier
* Block failure
* Chronic opioid, gabapentinoid use
* Severe kidney disfunction

Minimum Eligible Age

14 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No