Treatment of Transsphicteric Fistula-in-ano by Method of Laser Thermoobliteration(FiLaC™).

NCT ID: NCT03690934

Last Updated: 2018-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-23

Study Completion Date

2020-08-31

Brief Summary

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This is a randomized, controlled, parallel study to compare the results of treatment for patients with transsphincteric fistulas-in-ano.

Detailed Description

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We are planning to eroll 120 patients in this study,the duration of the stady be 3 years. Each of two groups will include 60 people. Pationts in the first group will be assigned to get treatment of the fistula-in-ano by laser thermo-obliteration (FiLAC™), patietns of the second group will forego monopolar coagulation of the fistulas tract with suturing the internal fistulas opening.

Conditions

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Anal Fistula

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Assignment
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Fistula-tract laser closure (FiLAC™)

The treatment technique consists of laser coagulation of fistulous tract walls with a diode laser with a wavelength of 1470 nm, which leads to thermo-obliteration of the fistulous tract.

Group Type EXPERIMENTAL

Fistula-tract laser closure (FiLAC™)

Intervention Type PROCEDURE

The procedure was performed with a diode laser platform emitting laser energy of 15 W at a wavelength of 1470 nm by means of a radial fiber. For obliteration, the fistula track is treated with a continuous slow retraction of the laser fibre withdrawn at a rate of approximately 1 cm per 2-3s.

Fistula monopolar cogulation

The treatment technicque consists of monopolar coagulation of fistulous tract walls with suturing the internal fistulas opening.

Group Type ACTIVE_COMPARATOR

Monopolar coagulation of fistulous tract

Intervention Type PROCEDURE

The procedure was performed with a monopolar coagulator platform emitting monopolar coagulation. For obliteration, the fistula track is treated with a continuous slow retraction of the monopolar energy with suturing the internal fistulas opening.

Interventions

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Fistula-tract laser closure (FiLAC™)

The procedure was performed with a diode laser platform emitting laser energy of 15 W at a wavelength of 1470 nm by means of a radial fiber. For obliteration, the fistula track is treated with a continuous slow retraction of the laser fibre withdrawn at a rate of approximately 1 cm per 2-3s.

Intervention Type PROCEDURE

Monopolar coagulation of fistulous tract

The procedure was performed with a monopolar coagulator platform emitting monopolar coagulation. For obliteration, the fistula track is treated with a continuous slow retraction of the monopolar energy with suturing the internal fistulas opening.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Informed consent to the study;
2. Patients with high transsphincteric fistula (\>1/3), suprasphincteric fistula whithout abscesses;
3. The presence of a formed fistulous tract \> 2 cm in length.

Exclusion Criteria

1. Suprasphincteric fistula with abscesses or infiltrates;
2. Extrasphincteric fistula;
3. Length of fistula tract \< 2 cm;
4. The presence of sever scars in the region of internal fistula opening, wide fistula opening \> 5 mm;
5. Crohn's fistulae
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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State Scientific Centre of Coloproctology, Russian Federation

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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State Scientific Centre of Coloproctology

Moscow, , Russia

Site Status RECRUITING

Countries

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Russia

Central Contacts

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Ivan Kostarev, MD

Role: CONTACT

+7-499-199-63-98

Facility Contacts

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Ivan Kostarev, MD

Role: primary

Other Identifiers

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74

Identifier Type: -

Identifier Source: org_study_id

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