Interest of the T2 * Sequence in MRI for the Diagnosis of Migraine Aura in the Acute Phase.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-12-22

Study Completion Date

2020-12-11

Brief Summary

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investigators hypothesize that T2 \* vein abnormalities are frequent and are specific to the migraine aura.

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Detailed Description

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The diagnosis of migraine aura is now based solely on clinical criteria and the assertion of the diagnosis on these clinical criteria alone proves difficult in the acute phase. Added to this difficulty, the symptomatology of a migraine aura can sometimes be similar to that of a stroke, so a diagnosis can be poorly established, resulting in poor patient care. The possibility of making the positive diagnosis of migraine aura on a routine MRI sequence, T2 \*, would be an important advance for the management of these patients

Conditions

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Migraine Aura

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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with migraine aura.

patient with migraine aura detected by MRI, then MRI control 3 month after

Group Type OTHER

MRI

Intervention Type COMBINATION_PRODUCT

Routine MRI with all the sequences performed for the management of acute neurological deficit in the Toulouse Neuro Vascular Unit (diffusion, FLAIR, T2 \*, vascular sequences (AngioRM and TOF) and perfusion).

MRI control

Intervention Type DIAGNOSTIC_TEST

MRI with all the sequences performed for the management of acute neurological deficit in the Toulouse Neuro Vascular Unit (diffusion, FLAIR, T2 \*, vascular sequences (AngioRM and TOF) and perfusion)

without migraine aura

patient without migraine aura detected by MRI, then telephone consultation 3 month after

Group Type OTHER

telephone consultation

Intervention Type OTHER

telephone consultation

Interventions

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MRI

Routine MRI with all the sequences performed for the management of acute neurological deficit in the Toulouse Neuro Vascular Unit (diffusion, FLAIR, T2 \*, vascular sequences (AngioRM and TOF) and perfusion).

Intervention Type COMBINATION_PRODUCT

MRI control

MRI with all the sequences performed for the management of acute neurological deficit in the Toulouse Neuro Vascular Unit (diffusion, FLAIR, T2 \*, vascular sequences (AngioRM and TOF) and perfusion)

Intervention Type DIAGNOSTIC_TEST

telephone consultation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 to 55 years
* Admitted to the Neuro-Vascular Intensive Care Unit for Acute Focused Neurological Symptoms and MRI

* less than 4 hours 30 minutes after onset of symptoms if symptoms persist during admission
* less than two hours after the disappearance of symptoms if the patient arrives asymptomatic
* Affiliated to a social protection scheme.
* Having given their informed consent

Exclusion Criteria

* Patients with neurological signs pointing to vertebrobasilar localization (vertigo, diplopia) or with a disorder of consciousness
* Presence of recent explanatory abnormalities on the MRI to make a diagnosis compatible with the initial neurological symptomatology (visible stroke in diffusion, cerebral hemorrhage, tumor, arteriovenous malformations).
* Potential strong cause of stroke known or discovered at the arrival of the patient, in particular stenosis of a cervical or intracranial artery upstream of the cerebral zone may correspond to the symptoms and emboligenic heart disease type atrial fibrillation.
* Pregnant women - Patients with a contraindication for MRI.
* Patients benefiting from a system of legal protection (tutelage,

Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No