The Relationship Between Autobiographical Memory and Motivation

NCT ID: NCT03677635

Last Updated: 2025-07-18

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

31 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-18

Study Completion Date

2020-02-19

Brief Summary

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People with a diagnosis of psychosis often experience low motivation and pleasure when thinking about doing future activities. This leads, quite understandably, to doing fewer activities they used to enjoy and not taking up opportunities to do new activities. One model suggests that this may be partly due to difficulties using memories of previous events to help boost motivation and anticipation before a future activity. Research shows that people with psychosis may recall previous events in less detail. These memories therefore may not be as helpful as they could be for motivation. This study will investigate this by asking people with experience of psychosis and low motivation who are seen by a care team in South London and Maudsley NHS Trust to attend two research sessions. In the first session the participants will be asked to recall memories of events from their lives and the researcher will assess how detailed the memories are and how much the participant refers to the past and future. Alongside this task the participants will also be asked to complete measures of symptoms such as low pleasure and motivation as well as a measure of depression. These will be used to find out if the detail and specificity of the memories are related to these symptoms in people with psychosis. The second half of the study will then investigate whether additional prompts to support positive memory retrieval can increase the specificity of this and subsequently improve mood, motivation and self-belief. Participants will be randomised to one of two groups. The clinical group will be guided through their memory recall using prompts and a control group will be asked to recall positive memories without prompts. If the investigators show that supporting memory recall is beneficial then memories for past events may be an important target for future therapies.

Detailed Description

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Conditions

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Psychosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Intervention

Guided autobiographical memory recall to enhance specificity and links to the future.

Group Type EXPERIMENTAL

Guided Autobiographical Memory Recall

Intervention Type BEHAVIORAL

Participants are asked to recall positive autobiographical memories with the assistance of prompts to promote specificity, generalisability and links to the future. The participants will also view a 5min psychoeducation video on the subject of memory specificity and motivation.

Control

Recall without prompts or psychoeducation video.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Guided Autobiographical Memory Recall

Participants are asked to recall positive autobiographical memories with the assistance of prompts to promote specificity, generalisability and links to the future. The participants will also view a 5min psychoeducation video on the subject of memory specificity and motivation.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* A diagnosis of non-affective psychosis (as determined by medical records).
* Above 18yrs old.
* A score of at least 18 on the Clinical Assessment Interview for Negative Symptoms.
* A sufficient command of the English language to engage with the research materials

Exclusion Criteria

* Lack of capacity to provide informed consent.
* Primary diagnosis of intellectual disability, head injury, substance misuse or known organic cause of psychosis
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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King's College London

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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South London and Maudsley NHS Trust

London, , United Kingdom

Site Status

Institute of Psychiatry, Psychology & Neuroscience, KCL

London, , United Kingdom

Site Status

Countries

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United Kingdom

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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214063

Identifier Type: -

Identifier Source: org_study_id

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