Trial Outcomes & Findings for The Relationship Between Autobiographical Memory and Motivation (NCT NCT03677635)

Results Overview

A rating on a visual analogue scale assessing motivation to repeat the same activity recalled in the future. The scale is rated from 0-100 and a higher score indicated better outcome.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

31 participants

Primary outcome timeframe

Immediately after completing the intervention

Results posted on

2025-07-18

Participant Flow

A total of 31 people with a diagnosis of non-affective psychosis participated between May 2017-Feb 2018.

Participant milestones

Participant milestones
Measure	Intervention Guided autobiographical memory recall to enhance specificity and links to the future.	Control Recall without prompts or psychoeducation video.
Overall Study STARTED	21	10
Overall Study COMPLETED	21	10
Overall Study NOT COMPLETED	0	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

The Relationship Between Autobiographical Memory and Motivation

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Intervention n=21 Participants Guided autobiographical memory recall to enhance specificity and links to the future.	Control n=10 Participants Recall without prompts or psychoeducation video.	Total n=31 Participants Total of all reporting groups
Age, Continuous	38.62 Years STANDARD_DEVIATION 10.98 • n=5 Participants	41.10 Years STANDARD_DEVIATION 9.09 • n=7 Participants	39.55 Years STANDARD_DEVIATION 10.83 • n=5 Participants
Sex: Female, Male Female	5 Participants n=5 Participants	2 Participants n=7 Participants	7 Participants n=5 Participants
Sex: Female, Male Male	16 Participants n=5 Participants	8 Participants n=7 Participants	24 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	0 Participants n=5 Participants	1 Participants n=7 Participants	1 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	21 Participants n=5 Participants	9 Participants n=7 Participants	30 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Clinical Assessment Interview for Negative Symptoms	24.1 units on a scale STANDARD_DEVIATION 6.37 • n=5 Participants	17.1 units on a scale STANDARD_DEVIATION 6.82 • n=7 Participants	21.73 units on a scale STANDARD_DEVIATION 7.04 • n=5 Participants

PRIMARY outcome

Timeframe: Immediately after completing the intervention

A rating on a visual analogue scale assessing motivation to repeat the same activity recalled in the future. The scale is rated from 0-100 and a higher score indicated better outcome.

Outcome measures

Outcome measures
Measure	Intervention n=21 Participants Guided autobiographical memory recall to enhance specificity and links to the future.	Control n=10 Participants Recall without prompts or psychoeducation video.
Post-Intervention Motivation Score	81.01 units on a scale Standard Error 4.15 • Interval 69.21 to 85.86	72.89 units on a scale Standard Error 5.79 • Interval 65.12 to 88.38

SECONDARY outcome

Timeframe: Immediately after completing the intervention

A rating on a visual analogue scale assessing how pleasant that activity is anticipated to be if repeated. The scale is rated from 0-100 and a higher score indicated better outcome.

Outcome measures

Outcome measures
Measure	Intervention n=21 Participants Guided autobiographical memory recall to enhance specificity and links to the future.	Control n=10 Participants Recall without prompts or psychoeducation video.
Post-Intervention Anticipatory Pleasure	84.35 units on a scale Standard Error 3.05	86.58 units on a scale Standard Error 4.76

Adverse Events

Intervention

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Control

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr Clementine Edwards

King's College London

Phone: 07557866053

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place